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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Aminopeptidase PILS/ARTS1 Protein, CF
catalog :
2334-ZN-010
quantity :
10 ug
price :
514 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Laura M, Ronan G, Vy L, Valentin G, Omar C, Virgyl C, et al. Modulators of hERAP2 discovered by high-throughput screening. Eur J Med Chem. 2021;211:113053 pubmed publisher
Textoris Taube K, Cammann C, Henklein P, Topfstedt E, Ebstein F, Henze S, et al. ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope. Eur J Immunol. 2020;50:270-283 pubmed publisher
Kourjian G, Xu Y, Mondesire Crump I, Shimada M, Gourdain P, Le Gall S. Sequence-specific alterations of epitope production by HIV protease inhibitors. J Immunol. 2014;192:3496-506 pubmed publisher
Krige D, Needham L, Bawden L, Flores N, Farmer H, Miles L, et al. CHR-2797: an antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells. Cancer Res. 2008;68:6669-79 pubmed publisher
product information
brand :
R&D Systems
master code :
2334-ZN
SKU :
2334-ZN-010
product name :
Recombinant Human Aminopeptidase PILS/ARTS1 Protein, CF
unit size :
10 ug
seo description :
The Recombinant Human Aminopeptidase PILS/ARTS1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Aminopeptidase PILS/ARTS1 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Aminopeptidase PILS/ARTS1
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.
conjugate :
Unconjugated
dilution :
Enzyme Activity
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
108 kDa, reducing conditions
theoretical molecular weight :
105 kDa
gene symbol :
ERAP1
details of functionality :
Measured by its ability to cleave the fluorogenic peptide substrate, Leu-AMC. The specific activity is 125 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
EAW96077
applications :
Enzyme Activity
source :
NS0-derived Recombinant Human Aminopeptidase PILS/ARTS1 Protein, CF
USD :
514 USD
alt names :
Adipocyte-derived leucine aminopeptidase, A-LAP, A-LAPALAP, Aminopeptidase PILS, ARTS1, ARTS1aminopeptidase regulator of TNFR1 shedding, ARTS-1PILSAP, EC 3.4.11, EC 3.4.11.-, EC 3.4.11.1, endoplasmic reticulum aminopeptidase 1, endoplasmic reticulum aminopeptidase associated with antigen processing, ERAAP1, ERAP1, KIAA0525APPILS, PILS-AP, PILS-APERAAP, Puromycin-insensitive leucyl-specific aminopeptidase, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.