product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Testican 1/SPOCK1 Protein, CF
catalog :
2327-PI-050
quantity :
50 ug
price :
432 USD
more info or order :
citations: 2
Reference
Du Z, Lin Z, Wang Z, Liu D, Tian D, Xia L. SPOCK1 overexpression induced by platelet-derived growth factor-BB promotes hepatic stellate cell activation and liver fibrosis through the integrin α5β1/PI3K/Akt signaling pathway. Lab Invest. 2020;100:1042-1056 pubmed publisher
Krishnatry A, Brazeau D, Fung H. Broad regulation of matrix and adhesion molecules in THP-1 human macrophages by nitroglycerin. Nitric Oxide. 2010;22:11-7 pubmed publisher
product information
brand :
R&D Systems
master code :
2327-PI
SKU :
2327-PI-050
product name :
Recombinant Human Testican 1/SPOCK1 Protein, CF
unit size :
50 ug
seo description :
The Recombinant Human Testican 1/SPOCK1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Testican 1/SPOCK1 Protein, CF has been validated for the following applications: Inhibition Activity.
target :
Testican 1/SPOCK1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Inhibition Activity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
50-56 kDa, reducing conditions
theoretical molecular weight :
48 kDa
gene symbol :
SPOCK1
details of functionality :
Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC (Catalog # ES008 ). The IC50 value is 10 nM, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q08629
applications :
Inhibition Activity
source :
NS0-derived Recombinant Human Testican 1/SPOCK1 Protein, CF
USD :
432 USD
alt names :
FLJ37170, Protein SPOCK, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1, SPOCK1, SPOCKcwcv and kazal-like domains proteoglycan (testican), TIC1, TICN1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.