Recombinant Mouse TSG-6 Protein, CF | R&D Systems 2326-TS-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TSG-6 Protein, CF

catalog :

2326-TS-050

quantity :

50 ug

price :

541 USD

citations: 9

Reference
Di Santo C, La Russa D, Greco R, Persico A, Zanaboni A, Bagetta G, et al. Characterization of the Involvement of Tumour Necrosis Factor (TNF)-α-Stimulated Gene 6 (TSG-6) in Ischemic Brain Injury Caused by Middle Cerebral Artery Occlusion in Mouse. Int J Mol Sci. 2023;24: pubmed publisher
Broeren M, Di Ceglie I, Bennink M, van Lent P, van den Berg W, Koenders M, et al. Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation. Peerj. 2018;6:e4771 pubmed publisher
Dong Y, Arif A, Olsson M, Cali V, Hardman B, Dosanjh M, et al. Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-?, interleukin-12 or upregulate co-stimulatory molecules in dendritic cells or macrophages. Sci Rep. 2016;6:36928 pubmed publisher
Abbadi A, Lauer M, Swaidani S, Wang A, Hascall V. Hyaluronan Rafts on Airway Epithelial Cells. J Biol Chem. 2016;291:1448-55 pubmed publisher
Torihashi S, Ho M, Kawakubo Y, Komatsu K, Nagai M, Hirayama Y, et al. Acute and temporal expression of tumor necrosis factor (TNF)-Î±-stimulated gene 6 product, TSG6, in mesenchymal stem cells creates microenvironments required for their successful transplantation into muscle tissue. J Biol Chem. 2015;290:22771-81 pubmed publisher
Fujita R, Tamai K, Aikawa E, Nimura K, Ishino S, Kikuchi Y, et al. Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice. Stem Cells. 2015;33:962-75 pubmed publisher
Liu Y, Zhang R, Yan K, Chen F, Huang W, Lv B, et al. Mesenchymal stem cells inhibit lipopolysaccharide-induced inflammatory responses of BV2 microglial cells through TSG-6. J Neuroinflammation. 2014;11:135 pubmed publisher
Wang N, Li Q, Zhang L, Lin H, Hu J, Li D, et al. Mesenchymal stem cells attenuate peritoneal injury through secretion of TSG-6. PLoS ONE. 2012;7:e43768 pubmed publisher
Tuo J, Cao X, Shen D, Wang Y, Zhang J, Oh J, et al. Anti-inflammatory recombinant TSG-6 stabilizes the progression of focal retinal degeneration in a murine model. J Neuroinflammation. 2012;9:59 pubmed publisher

product information

master code :

2326-TS

SKU :

2326-TS-050

product name :

Recombinant Mouse TSG-6 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse TSG-6 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse TSG-6 Protein, CF has been validated for the following applications: Binding Activity.

target :

TSG-6

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

39 kDa, reducing conditions

theoretical molecular weight :

29.8 kDa

gene symbol :

Tnfaip6

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmTSG-6 can bind biotinylated Hyaluronan with an estimated KD 1 nM.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O08859

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse TSG-6 protein Trp18-Leu275, with a C-terminal 6-His tag

source short :

NS0

USD :

541 USD

alt names :

Hyaluronate-binding protein, TNF alpha-induced protein 6, TNFAIP6, TNF-stimulated gene 6 protein, TSG6, TSG-6tumor necrosis factor alpha-inducible protein 6, TSG6tumor necrosis factor-inducible gene 6 protein, Tumor necrosis factor alpha-induced protein 6, tumor necrosis factor, alpha-induced protein 6, tumor necrosis factor-stimulated gene-6 protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.