product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Chemerin (aa 17-156) Protein, CF
catalog :
2325-CM-025/CF
quantity :
25 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 14
Reference
Al Delbany D, Robert V, Dubois Vedrenne I, Del Prete A, Vernimmen M, Radi A, et al. Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis. Cancers (Basel). 2021;13: pubmed publisher
Dubois Vedrenne I, Al Delbany D, De Henau O, Robert V, Vernimmen M, Langa F, et al. The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis. Oncotarget. 2021;12:1903-1919 pubmed publisher
Han L, Zhang Y, Wan S, Wei Q, Shang W, Huang G, et al. Loss of chemerin triggers bone remodeling in vivo and in vitro. Mol Metab. 2021;53:101322 pubmed publisher
Kim I, Park H, Hwang I, Moon D, Yun H, Lee E, et al. Discovery of chemerin as the new chemoattractant of human mesenchymal stem cells. Cell Biosci. 2021;11:120 pubmed publisher
Liang Z, Han L, Sun D, Chen Y, Wu Q, Zhang L, et al. Chemerin-induced macrophages pyroptosis in fetal brain tissue leads to cognitive disorder in offspring of diabetic dams. J Neuroinflammation. 2019;16:226 pubmed publisher
Ramos Junior E, Leite G, Carmo Silva C, Taira T, Neves K, Colón D, et al. Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice. J Bone Miner Res. 2017;32:974-984 pubmed publisher
Klose R, Krzywinska E, Castells M, Gotthardt D, Putz E, Kantari Mimoun C, et al. Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia. Nat Commun. 2016;7:12528 pubmed publisher
Yang Y, Ren L, Sun L, Huang C, Xiao T, Wang B, et al. The role of GPR1 signaling in mice corpus luteum. J Endocrinol. 2016;230:55-65 pubmed publisher
Graham K, Zhang J, Lewén S, BURKE T, Dang T, Zoudilova M, et al. A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease. PLoS ONE. 2014;9:e112925 pubmed publisher
Gonzalvo Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, et al. Endothelial cell-derived chemerin promotes dendritic cell transmigration. J Immunol. 2014;192:2366-73 pubmed publisher
Pachynski R, Zabel B, Kohrt H, Tejeda N, Monnier J, Swanson C, et al. The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses. J Exp Med. 2012;209:1427-35 pubmed publisher
Cash J, Christian A, Greaves D. Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner. J Immunol. 2010;184:5315-24 pubmed publisher
Luangsay S, Wittamer V, Bondue B, De Henau O, Rouger L, Brait M, et al. Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model. J Immunol. 2009;183:6489-99 pubmed publisher
Cash J, Hart R, Russ A, Dixon J, Colledge W, Doran J, et al. Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med. 2008;205:767-75 pubmed publisher
product information
master code :
2325-CM/CF
SKU :
2325-CM-025/CF
product name :
Recombinant Mouse Chemerin (aa 17-156) Protein, CF
unit size :
25 ug
description :
The Recombinant Mouse Chemerin (aa 17-156) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse Chemerin (aa 17-156) Protein, CF has been validated for the following applications: Bioactivity.
target :
Chemerin
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
18 kDa, reducing conditions
theoretical molecular weight :
16 kDa
gene symbol :
Rarres2
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human ChemR23. The ED50 for this effect is 6-30 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_082128
applications :
Bioactivity
source long :
E. coli -derived mouse Chemerin protein Thr17-Ser156
source short :
E. coli
USD :
432 USD
alt names :
chemerin, RARRES2, RAR-responsive protein TIG2, retinoic acid receptor responder (tazarotene induced) 2, retinoic acid receptor responder protein 2, Tazarotene-induced gene 2 protein, TIG-2, TIG2HP10433
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.