This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Chemerin Protein
catalog :
2324-CM
quantity :
25 ug
price :
329 USD
citations: 11
Reference
Kumar V, Lajevic M, Pandrala M, Jacobo S, Malhotra S, Zabel B. Novel CMKLR1 Inhibitors for Application in Demyelinating Disease. Sci Rep. 2019;9:7178 pubmed publisher
Shang J, Wang L, Zhang Y, Zhang S, Ning L, Zhao J, et al. Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy. J Cell Mol Med. 2019;23:3417-3428 pubmed publisher
Momenpour A, Lima P, Chen Y, Tzeng C, Tsang B, Anis H. Surface-enhanced Raman scattering for the detection of polycystic ovary syndrome. Biomed Opt Express. 2018;9:801-817 pubmed publisher
Liu Chittenden Y, Jain M, Gaskins K, Wang S, Merino M, Kotian S, et al. RARRES2 functions as a tumor suppressor by promoting β-catenin phosphorylation/degradation and inhibiting p38 phosphorylation in adrenocortical carcinoma. Oncogene. 2017;36:3541-3552 pubmed publisher
Toulany J, Parlee S, Sinal C, Slayter K, McNeil S, Goralski K. CMKLR1 activation ex vivo does not increase proportionally to serum total chemerin in obese humans. Endocr Connect. 2016;5:70-81 pubmed
Kumar J, Kandola S, Tiszlavicz L, Reisz Z, Dockray G, Varro A. The role of chemerin and ChemR23 in stimulating the invasion of squamous oesophageal cancer cells. Br J Cancer. 2016;114:1152-9 pubmed publisher
Kumar J, Holmberg C, Kandola S, Steele I, Hegyi P, Tiszlavicz L, et al. Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells. PLoS ONE. 2014;9:e104877 pubmed publisher
Doyle J, Krishnaji S, Zhu G, Xu Z, Heller D, Ji R, et al. Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain. J Biol Chem. 2014;289:13385-96 pubmed publisher
Zhou J, Liao D, Zhang S, Cheng N, He H, Ye R. Chemerin C9 peptide induces receptor internalization through a clathrin-independent pathway. Acta Pharmacol Sin. 2014;35:653-63 pubmed publisher
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
Du X, Zabel B, Myles T, Allen S, Handel T, Lee P, et al. Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. J Biol Chem. 2009;284:751-8 pubmed publisher
product information
brand :
R&D Systems
master code :
2324-CM
SKU :
2324-CM-025
product name :
Recombinant Human Chemerin Protein
description :
The Recombinant Human Chemerin Protein from R&D Systems is derived from E. coli. The Recombinant Human Chemerin Protein has been validated for the following applications: Bioactivity.
target :
Chemerin
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
theoretical molecular weight :
16 kDa
gene symbol :
RARRES2
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human ChemR23. The ED50 for this effect is 4-20 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
2324-CM
accessionNumbers :
Q99969
applications :
Bioactivity
source :
E. coli -derived human Chemerin protein Glu21-Ser157, with an N-terminal Met
2020 USD :
329
2021 USD :
329 USD
alt names :
chemerin, RARRES2, RAR-responsive protein TIG2, retinoic acid receptor responder (tazarotene induced) 2, retinoic acid receptor responder protein 2, Tazarotene-induced gene 2 protein, TIG-2, TIG2HP10433
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.