Recombinant Human Chemerin Protein, CF | R&D Systems 2324-CM-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Chemerin Protein, CF

catalog :

2324-CM-025/CF

quantity :

25 ug

price :

400 USD

more info or order :

R&D Systems product webpage

citations: 13

Reference
Chen Y, Liu Z, Gong P, Zhang H, Chen Y, Yao S, et al. The Chemerin/CMKLR1 Axis Is Involved in the Recruitment of Microglia to Aβ Deposition through p38 MAPK Pathway. Int J Mol Sci. 2022;23: pubmed publisher
Dubois Vedrenne I, Al Delbany D, De Henau O, Robert V, Vernimmen M, Langa F, et al. The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis. Oncotarget. 2021;12:1903-1919 pubmed publisher
Kim H, Lee J, Lee S, Song N, Son S, Kim K, et al. Chemerin Treatment Inhibits the Growth and Bone Invasion of Breast Cancer Cells. Int J Mol Sci. 2020;21: pubmed publisher
Kumar V, Lajevic M, Pandrala M, Jacobo S, Malhotra S, Zabel B. Novel CMKLR1 Inhibitors for Application in Demyelinating Disease. Sci Rep. 2019;9:7178 pubmed publisher
Shang J, Wang L, Zhang Y, Zhang S, Ning L, Zhao J, et al. Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy. J Cell Mol Med. 2019;23:3417-3428 pubmed publisher
Momenpour A, Lima P, Chen Y, Tzeng C, Tsang B, Anis H. Surface-enhanced Raman scattering for the detection of polycystic ovary syndrome. Biomed Opt Express. 2018;9:801-817 pubmed publisher
Toulany J, Parlee S, Sinal C, Slayter K, McNeil S, Goralski K. CMKLR1 activation ex vivo does not increase proportionally to serum total chemerin in obese humans. Endocr Connect. 2016;5:70-81 pubmed
Kumar J, Kandola S, Tiszlavicz L, Reisz Z, Dockray G, Varro A. The role of chemerin and ChemR23 in stimulating the invasion of squamous oesophageal cancer cells. Br J Cancer. 2016;114:1152-9 pubmed publisher
Kumar J, Holmberg C, Kandola S, Steele I, Hegyi P, Tiszlavicz L, et al. Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells. PLoS ONE. 2014;9:e104877 pubmed publisher
Doyle J, Krishnaji S, Zhu G, Xu Z, Heller D, Ji R, et al. Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain. J Biol Chem. 2014;289:13385-96 pubmed publisher
Zhou J, Liao D, Zhang S, Cheng N, He H, Ye R. Chemerin C9 peptide induces receptor internalization through a clathrin-independent pathway. Acta Pharmacol Sin. 2014;35:653-63 pubmed publisher
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
Du X, Zabel B, Myles T, Allen S, Handel T, Lee P, et al. Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. J Biol Chem. 2009;284:751-8 pubmed publisher

product information

brand :

R&D Systems

master code :

2324-CM/CF

SKU :

2324-CM-025/CF

product name :

Recombinant Human Chemerin Protein, CF

unit size :

25 ug

seo description :

The Recombinant Human Chemerin Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Chemerin Protein, CF has been validated for the following applications: Bioactivity.

target :

Chemerin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

16 kDa

gene symbol :

RARRES2

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human ChemR23. The ED50 for this effect is 4-20 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q99969

applications :

Bioactivity

source :

E. coli-derived Recombinant Human Chemerin Protein, CF

USD :

400 USD

alt names :

chemerin, RARRES2, RAR-responsive protein TIG2, retinoic acid receptor responder (tazarotene induced) 2, retinoic acid receptor responder protein 2, Tazarotene-induced gene 2 protein, TIG-2, TIG2HP10433

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage