Recombinant Human FGF acidic/FGF1 (aa 16-155) Protein, CF | R&D Systems 232-FA-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF acidic/FGF1 (aa 16-155) Protein, CF

catalog :

232-FA-025/CF

quantity :

25 ug

price :

219 USD

more info or order :

R&D Systems product webpage

citations: 20

Reference
Shinmyo Y, Saito K, Hamabe Horiike T, Kameya N, Ando A, Kawasaki K, et al. Localized astrogenesis regulates gyrification of the cerebral cortex. Sci Adv. 2022;8:eabi5209 pubmed publisher
Huang H, Yang C, Yang C. Fibroblast Growth Factor Type 1 Ameliorates High-Glucose-Induced Oxidative Stress and Neuroinflammation in Retinal Pigment Epithelial Cells and a Streptozotocin-Induced Diabetic Rat Model. Int J Mol Sci. 2021;22: pubmed publisher
Toba Y, Kiso A, Nakamae S, Sakurai F, Takayama K, Mizuguchi H. FGF signal is not required for hepatoblast differentiation of human iPS cells. Sci Rep. 2019;9:3713 pubmed publisher
Taguchi A, Nishinakamura R. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:730-746.e6 pubmed publisher
Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, et al. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med. 2015;21:530-6 pubmed publisher
Tucker B, Mullins R, Streb L, Anfinson K, Eyestone M, Kaalberg E, et al. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. elife. 2013;2:e00824 pubmed publisher
Tucker B, Anfinson K, Mullins R, Stone E, Young M. Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med. 2013;2:16-24 pubmed publisher
Luo X, Hutley L, Webster J, Kim Y, Liu D, Newell F, et al. Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors. Diabetes. 2012;61:124-36 pubmed publisher
Roelandt P, Pauwelyn K, Sancho Bru P, Subramanian K, Bose B, Ordovas L, et al. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. PLoS ONE. 2010;5:e12101 pubmed publisher
Darby S, Murphy T, Thomas H, Robson C, Leung H, Mathers M, et al. Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is downregulated in aggressive clinical disease. Br J Cancer. 2009;101:1891-9 pubmed publisher
Zhang P, Nelson S, Bagby G, Siggins R, Shellito J, Welsh D. The lineage-c-Kit+Sca-1+ cell response to Escherichia coli bacteremia in Balb/c mice. Stem Cells. 2008;26:1778-86 pubmed publisher
Patel V, Likar K, Zisman Rozen S, Cowherd S, Lassiter K, Sher I, et al. Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation. J Biol Chem. 2008;283:9308-17 pubmed publisher
Patel V, Knox S, Likar K, Lathrop C, Hossain R, Eftekhari S, et al. Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis. Development. 2007;134:4177-86 pubmed
Lin B, Wang M, Blackmore C, Desnoyers L. Liver-specific activities of FGF19 require Klotho beta. J Biol Chem. 2007;282:27277-84 pubmed
Baharvand H, Hashemi S, Kazemi Ashtiani S, Farrokhi A. Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro. Int J Dev Biol. 2006;50:645-52 pubmed
Masih Khan E, Trudel S, Heise C, Li Z, Paterson J, Nadeem V, et al. MIP-1alpha (CCL3) is a downstream target of FGFR3 and RAS-MAPK signaling in multiple myeloma. Blood. 2006;108:3465-71 pubmed
Shin J, Min M, Larrieu Lahargue F, Canron X, Kunstfeld R, Nguyen L, et al. Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Mol Biol Cell. 2006;17:576-84 pubmed
Steinberg Z, Myers C, Heim V, Lathrop C, Rebustini I, Stewart J, et al. FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis. Development. 2005;132:1223-34 pubmed
Ohashi K, Waugh J, Dake M, Yokoyama T, Kuge H, Nakajima Y, et al. Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver diseases. Hepatology. 2005;41:132-40 pubmed
Dame M, Yu X, Garrido R, Bobrowski W, McDuffie J, Murphy H, et al. A stepwise method for the isolation of endothelial cells and smooth muscle cells from individual canine coronary arteries. In Vitro Cell Dev Biol Anim. 2003;39:402-6 pubmed

product information

brand :

R&D Systems

master code :

232-FA/CF

SKU :

232-FA-025/CF

product name :

Recombinant Human FGF acidic/FGF1 (aa 16-155) Protein, CF

unit size :

25 ug

seo description :

The Recombinant Human FGF acidic/FGF1 (aa 16-155) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human FGF acidic/FGF1 (aa 16-155) Protein, CF has been validated for the following applications: Bioactivity.

target :

FGF acidic/FGF1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MOPS, Na2SO4 and EDTA.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

15.5 kDa

gene symbol :

FGF1

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.015-0.15 ng/mL in the presence of 10 ╡g/mL of heparin.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_000791

applications :

Bioactivity

source :

E. coli-derived Recombinant Human FGF acidic/FGF1 (aa 16-155) Protein, CF

USD :

219 USD

alt names :

AFGF, alpha, alpha-ECGF, beta-ECGF, ECGF, ECGFB, ECGF-betaAcidic fibroblast growth factor, endothelial cell growth factor, beta, FGF acidic, FGF-1, FGFABeta-endothelial cell growth factor, FGF-alpha, fibroblast growth factor 1 (acidic), GLIO703, HBGF1, HBGF-1, heparin-binding growth factor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage