Recombinant Human FGF acidic/FGF1 (aa 2-155) Protein | R&D Systems 231-BC product information

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product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF acidic/FGF1 (aa 2-155) Protein

catalog :

231-BC

quantity :

25 ug

price :

239 USD

citations: 3

Reference
MacKenzie B, Korfei M, Henneke I, Sibinska Z, Tian X, Hezel S, et al. Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis. Respir Res. 2015;16:83 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Murasawa Y, Hayashi T, Wang P. The role of type V collagen fibril as an ECM that induces the motility of glomerular endothelial cells. Exp Cell Res. 2008;314:3638-53 pubmed publisher

product information

brand :

R&D Systems

master code :

231-BC

SKU :

231-BC-025

product name :

Recombinant Human FGF acidic/FGF1 (aa 2-155) Protein

description :

The Recombinant Human FGF acidic/FGF1 (aa 2-155) Protein from R&D Systems is derived from E. coli. The Recombinant Human FGF acidic/FGF1 (aa 2-155) Protein has been validated for the following applications: Bioactivity.

target :

FGF acidic/FGF1

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4, TCEP and EDTA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

17 kDa

gene symbol :

FGF1

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.015-0.15 ng/mL in the presence of 10 µg/mL of heparin.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

231-BC

accessionNumbers :

P05230.1

applications :

Bioactivity

source :

E. coli -derived human FGF acidic/FGF1 protein Ala2-Asp155

2020 USD :

239

2021 USD :

239 USD

alt names :

AFGF, alpha, alpha-ECGF, beta-ECGF, ECGF, ECGFB, ECGF-betaAcidic fibroblast growth factor, endothelial cell growth factor, beta, FGF acidic, FGF-1, FGFABeta-endothelial cell growth factor, FGF-alpha, fibroblast growth factor 1 (acidic), GLIO703, HBGF1, HBGF-1, heparin-binding growth factor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.