Recombinant Human Vitronectin Protein, CF | R&D Systems 2308-VN-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Vitronectin Protein, CF

catalog :

2308-VN-050

quantity :

50 ug

price :

286 USD

more info or order :

R&D Systems product webpage

citations: 11

Reference
Kang I, Jang J, Kim C. Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation. Sci Rep. 2020;10:7024 pubmed publisher
Gruet M, Cotton D, Coveney C, Boocock D, Wagner S, Komorowski L, et al. β2-Adrenergic Signalling Promotes Cell Migration by Upregulating Expression of the Metastasis-Associated Molecule LYPD3. Biology (Basel). 2020;9: pubmed publisher
Rajan A, Persson B, Frängsmyr L, Olofsson A, Sandblad L, Heino J, et al. Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Sci Rep. 2018;8:10019 pubmed publisher
Lee J, Berry C, Kim K, Sen P, Kim T, Carrer A, et al. Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling. Genes Dev. 2018;32:497-511 pubmed publisher
Tougan T, Edula J, Takashima E, Morita M, Shinohara M, Shinohara A, et al. Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5. Sci Rep. 2018;8:5052 pubmed publisher
Wolf D, Anto Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann J, et al. A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nat Commun. 2018;9:525 pubmed publisher
Levi L, Toyooka T, Patarroyo M, Frisan T. Bacterial genotoxins promote inside-out integrin β1 activation, formation of focal adhesion complexes and cell spreading. PLoS ONE. 2015;10:e0124119 pubmed publisher
Oliveira Ferrer L, Rosler K, Haustein V, Schroder C, Wicklein D, Maltseva D, et al. c-FOS suppresses ovarian cancer progression by changing adhesion. Br J Cancer. 2014;110:753-63 pubmed publisher
Zhang G, Panigrahy D, Mahakian L, Yang J, Liu J, Stephen Lee K, et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2013;110:6530-5 pubmed publisher
Chang M, Huang D, Ho F, Huang K, Lin W. PKC-dependent human monocyte adhesion requires AMPK and Syk activation. PLoS ONE. 2012;7:e40999 pubmed publisher
Franco M, Roswall P, Cortez E, Hanahan D, Pietras K. Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression. Blood. 2011;118:2906-17 pubmed publisher

product information

brand :

R&D Systems

master code :

2308-VN

SKU :

2308-VN-050

product name :

Recombinant Human Vitronectin Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human Vitronectin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Vitronectin Protein, CF has been validated for the following applications: Bioactivity.

target :

Vitronectin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

70-80 kDa, reducing conditions

theoretical molecular weight :

52.3 kDa

gene symbol :

VTN

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of B16-F1 mouse melanoma cells. When 5 x 104 cells/well are added to Vitronectin coated plates (5 ╡g/mL with 100 ╡L/well), approximately 55% will adhere after 30 minutes at 37 ░C. Optimal concentration depends on cell type as well as the application or research objectives.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAH05046.1

applications :

Bioactivity

source :

NS0-derived Recombinant Human Vitronectin Protein, CF

USD :

286 USD

alt names :

complement S-protein, epibolin, serum spreading factor, Serum-spreading factor, somatomedin B, S-protein, V75, vitronectin, vitronectin (serum spreading factor, somatomedin B, complement S-protein), VN, VNT, VTN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage