Recombinant Human Glypican 2 Protein, CF | R&D Systems 2304-GP-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Glypican 2 Protein, CF

catalog :

2304-GP-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Pascual Pasto G, McIntyre B, Hines M, Giudice A, Garcia Gerique L, Hoffmann J, et al. CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma. Nat Commun. 2024;15:7141 pubmed publisher
Balke Want H, Keerthi V, Gkitsas N, MANCINI A, Kurgan G, Fowler C, et al. Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing. Mol Cancer. 2023;22:100 pubmed publisher
Li N, Quan A, Li D, Pan J, Ren H, Hoeltzel G, et al. The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer. Nat Commun. 2023;14:1986 pubmed publisher
Br xe9 g xe8 re C, Fisch U, Halbeisen F, Schneider C, Dittmar T, Stricker S, et al. Doublecortin and Glypican-2 concentrations in the cerebrospinal fluid from infants are developmentally downregulated. PLoS ONE. 2023;18:e0279343 pubmed publisher
Lugert S, Kremer T, Jagasia R, Herrmann A, Aigner S, Giachino C, et al. Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis. Sci Rep. 2017;7:46543 pubmed publisher

product information

master code :

2304-GP

SKU :

2304-GP-050

product name :

Recombinant Human Glypican 2 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Glypican 2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Glypican 2 Protein, CF has been validated for the following applications: Binding Activity.

target :

Glypican 2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

50 - 60 kDa, non-reducing conditions

theoretical molecular weight :

59.2 kDa

gene symbol :

GPC2

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Glypican 2 at 4 ╡g/mL (100 ╡L/well) can bind Recombinant Human Midkine (Catalog # 258-MD ) with a linear range of 4-200 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q8N158

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human Glypican 2 protein Pro18-Ser553 & Ala359-Ser553, both with a C-terminal 6-His tag & Pro18-Ala359

source short :

NS0

USD :

432 USD

alt names :

2410016G05Rik, Cerebroglycan, GPC2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage