Recombinant Human IL-4R alpha Protein | R&D Systems 230-4R-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-4R alpha Protein

catalog :

230-4R-025

quantity :

25 ug

price :

525 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Shioji S, Imai S, Ando K, Kumagai K, Matsusue Y. Extracellular and intracellular mechanisms of mechanotransduction in three-dimensionally embedded rat chondrocytes. PLoS ONE. 2014;9:e114327 pubmed publisher
Wenzel S, Wilbraham D, Fuller R, Getz E, Longphre M. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet. 2007;370:1422-31 pubmed
Andrews A, Nasir T, Bucchieri F, Holloway J, Holgate S, Davies D. IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts. J Allergy Clin Immunol. 2006;118:858-65 pubmed

product information

brand :

R&D Systems

master code :

230-4R

SKU :

230-4R-025

product name :

Recombinant Human IL-4R alpha Protein

unit size :

25 ug

seo description :

The Recombinant Human IL-4R alpha Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human IL-4R alpha Protein has been validated for the following applications: Bioactivity.

target :

IL-4R alpha

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

30-35 kDa, reducing conditions

theoretical molecular weight :

24 kDa

gene symbol :

IL4R

details of functionality :

Measured by its ability to inhibit IL-4-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. Approximately 5-25 ng/mL of IL-4 R alpha will inhibit 50% of the biological response due to 0.2 ng/mL of recombinant human IL-4.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P24394

applications :

Bioactivity

source :

Sf 21 (baculovirus)-derived Recombinant Human IL-4R alpha Protein

USD :

525 USD

alt names :

CD124, CD124 antigen, IL-4 R alpha, IL-4 receptor subunit alpha, IL4R, IL4R alpha, IL-4R subunit alpha, IL-4RA, IL4RACD124, IL-4R-alpha, interleukin 4 receptor, interleukin-4 receptor alpha chain, interleukin-4 receptor subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage