Human Bax aa 3-16 Antibody | R & D Systems 2282-MC-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R & D Systems

product type :

antibody

product name :

Human Bax aa 3-16 Antibody

catalog :

2282-MC-100

quantity :

100 ug

price :

313 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

YTH-2D2

reactivity :

human

application :

western blot, immunoprecipitation

citations: 8

Published Application/Species/Dilution	Reference
western blot; human	Strauss G, Westhoff M, Fischer-Posovszky P, Fulda S, Schanbacher M, Eckhoff S, et al. 4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG. Cell Death Differ. 2008;15:332-43 pubmed
	Dunnill C, Ibraheem K, Mohamed A, Southgate J, Georgopoulos N. A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis. Oncogene. 2016;: pubmed publisher
	Hao J, Yu M, Liu F, Newland A, Jia L. Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells. Cancer Res. 2004;64:3607-16 pubmed
	Agrawal S, Liu F, Wiseman C, Shirali S, Liu H, Lillington D, et al. Increased proteasomal degradation of Bax is a common feature of poor prognosis chronic lymphocytic leukemia. Blood. 2008;111:2790-6 pubmed
	Liu F, Agrawal S, Movasaghi Z, Wyatt P, Rehman I, Gribben J, et al. Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib. Blood. 2008;112:3835-46 pubmed publisher
	Jia L, Patwari Y, Srinivasula S, Newland A, Fernandes-Alnemri T, Alnemri E, et al. Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis. Oncogene. 2001;20:4817-26 pubmed
	Oliver L, Mahe B, Grée R, Vallette F, Juin P. HA14-1, a small molecule inhibitor of Bcl-2, bypasses chemoresistance in leukaemia cells. Leuk Res. 2007;31:859-63 pubmed
	Liu F, Goff L, Hao J, Newland A, Jia L. Increase in the ratio of mitochondrial Bax/Bcl-XL induces Bax activation in human leukemic K562 cell line. Apoptosis. 2004;9:377-84 pubmed

product information

SKU :

2282-MC-100

category :

Primary Antibodies

unit size :

100 ug

product name :

Human Bax aa 3-16 Antibody

alt names :

apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4

buffer :

This antibody is provided as purified immunoglobulin from mouse ascites in 1X PBS containing 0.01% sodium azide.

clonality :

Monoclonal

clone :

YTH-2D2

conjugate :

Unconjugated

host :

Mouse

immunogen :

Human Bax, aa 3-16

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Anti-Bax (Clone YTH-2D2) cross reacts with human Bax.

storage :

Store at 4 °C.

gene symbol :

BAX

brand :

R&D Systems

target :

Bax

applications :

Western Blot, Immunoprecipitation

USD :

313 USD