Recombinant Canine SCF Protein | R&D Systems 2278-SC-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Canine SCF Protein

catalog :

2278-SC-025

quantity :

25 ug

price :

432 USD

citations: 5

Reference
Tani H, Miyamoto R, Noguchi S, Kurita S, Nagashima T, Michishita M, et al. A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis. BMC Vet Res. 2021;17:147 pubmed publisher
Makii R, Cook H, Louke D, Breitbach J, Jennings R, Premanandan C, et al. Characterization of WWOX expression and function in canine mast cell tumors and malignant mast cell lines. BMC Vet Res. 2020;16:415 pubmed publisher
Garton A, Seibel S, Lopresti Morrow L, Crew L, Janson N, Mandiyan S, et al. Anti-KIT Monoclonal Antibody Treatment Enhances the Antitumor Activity of Immune Checkpoint Inhibitors by Reversing Tumor-Induced Immunosuppression. Mol Cancer Ther. 2017;16:671-680 pubmed publisher
Bauer T, Olson E, Huo Y, Tuschong L, Allen J, Li Y, et al. Treatment of canine leukocyte adhesion deficiency by foamy virus vectors expressing CD18 from a PGK promoter. Gene Ther. 2011;18:553-9 pubmed publisher
Lin T, London C. A functional comparison of canine and murine bone marrow derived cultured mast cells. Vet Immunol Immunopathol. 2006;114:320-34 pubmed

product information

master code :

2278-SC

SKU :

2278-SC-025

product name :

Recombinant Canine SCF Protein

unit size :

25 ug

description :

The Recombinant Canine SCF Protein from R&D Systems is derived from E. coli. The Recombinant Canine SCF Protein has been validated for the following applications: Bioactivity.

target :

SCF/c-kit Ligand

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Canine

theoretical molecular weight :

18.5 kDa

gene symbol :

KITLG

details of functionality :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 1-3 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q06220

applications :

Bioactivity

source long :

E. coli -derived canine SCF/c-kit Ligand protein Lys26-Ala190, with an N-terminal Met

source short :

E. coli

USD :

432 USD

alt names :

c-kit Ligand, DCUA, DFNA69, DKFZp686F2250, familial progressive hyperpigmentation 2, FPH2, FPHH, KIT ligand, Kitl, KITLG, KL-1, Mast cell growth factor, MGF, MGFSHEP7, SCFStem cell factor, SFc-Kit ligand, SHEP7, SLF, steel factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.