product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse FGFR4 Fc Chimera Protein, CF
catalog :
2265-FR-050
quantity :
50 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Bartz R, Fukuchi K, Ohtsuka T, Lange T, Grüner K, Watanabe I, et al. Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity. Mol Cancer Ther. 2019;18:1832-1843 pubmed publisher
product information
brand :
R&D Systems
master code :
2265-FR
SKU :
2265-FR-050
product name :
Recombinant Mouse FGFR4 Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse FGFR4 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse FGFR4 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
FGFR4
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
90-100 kDa, reducing conditions
theoretical molecular weight :
66 kDa (monomer)
gene symbol :
Fgfr4
details of functionality :
Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is typically 7-35 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q03142
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse FGFR4 Fc Chimera Protein, CF
USD :
456 USD
alt names :
CD334, CD334 antigen, EC 2.7.10, EC 2.7.10.1, FGF R4, FGFR-4, fibroblast growth factor receptor 4, JTK2hydroxyaryl-protein kinase, MGC20292, protein-tyrosine kinase, TKF, tyrosine kinase related to fibroblast growth factor receptor, tyrosylprotein kinase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.