Recombinant Human FGF-12 Protein | R&D Systems 2246-FG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF-12 Protein

catalog :

2246-FG

quantity :

25 ug

price :

269 USD

citations: 2

Reference
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher

product information

brand :

R&D Systems

master code :

2246-FG

SKU :

2246-FG-025

product name :

Recombinant Human FGF-12 Protein

description :

The Recombinant Human FGF-12 Protein from R&D Systems is derived from E. coli. The Recombinant Human FGF-12 Protein has been validated for the following applications: Binding Activity.

target :

FGF-12

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4 and EDTA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

20.4 kDa

gene symbol :

FGF12

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human FGFR4 Fc Chimera (Catalog # 685-FR ) is immobilized at 2 µg/mL, 100 µL/well, Recombinant FGF-12 binds with an ED50 of 3-18 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

2246-FG

accessionNumbers :

NP_004104

applications :

Binding Activity

source :

E. coli -derived human FGF-12 protein Met1-Thr181

2020 USD :

239

2021 USD :

269 USD

alt names :

FGF12, FGF-12, FGF12B, FHF1, FHF-1, FHF1Fibroblast growth factor homologous factor 1, fibroblast growth factor 12, fibroblast growth factor 12B, fibroblast growth factor FGF-12b, Myocyte-activating factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.