This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CEACAM-1/CD66a Protein, CF
catalog :
2244-CM
quantity :
50 ug
price :
349 USD
citations: 1
Reference
Rahmoun M, Moles J, Pedretti N, Mathieu M, Fremaux I, Raison Peyron N, et al. Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils. J Invest Dermatol. 2009;129:671-81 pubmed publisher
product information
brand :
R&D Systems
master code :
2244-CM
SKU :
2244-CM-050
product name :
Recombinant Human CEACAM-1/CD66a Protein, CF
description :
The Recombinant Human CEACAM-1/CD66a Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CEACAM-1/CD66a Protein, CF has been validated for the following applications: Bioactivity.
target :
CEACAM1/CD66a
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
100-130 kDa, reducing conditions
theoretical molecular weight :
44.6 kDa
gene symbol :
CEACAM1
details of functionality :
Measured by its ability to inhibit IL-2 secretion by HuT 78 human cutaneous T cell lymphoma cells Chen, C.J. and J.E. Shively (2004) J. Immunol. 172 :3544. rhCEACAM-1 at concentrations higher than 1 µg/mL reduces anti-CD3 (immobilized at 10 µg/mL) induced IL-2 production by 60-70%. The ED50 for rhCEACAM-1 inhibition of anti-CD3 induced IL-2 production is 0.05-0.2 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
2244-CM
accessionNumbers :
P13688
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human CEACAM-1/CD66a protein Gln35-Gly428, with a C-terminal 10-His tag
2020 USD :
349
2021 USD :
349 USD
alt names :
antigen CD66, BGP1, BGP-1, BGP1BGPBiliary glycoprotein 1, BGPI, Biliary Glycoprotein 1, biliary glycoprotein adhesion molecule, carcinoembryonic antigen-related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliaryglycoprotein), CD66a, CD66a antigen, Cea-1, CEACAM1, Hv-1, Hv-2, MHVR
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.