product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human KIR2DL4/CD158d Fc Chimera Protein, CF
catalog :
2238-KR-050
quantity :
50 ug
price :
518 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Fittje P, H x153 lzemer A, Garcia Beltran W, Vollmers S, Niehrs A, Hagemann K, et al. HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells. PLoS Pathog. 2022;18:e1010572 pubmed publisher
Ryser S, Estelles A, Tenorio E, KAUVAR L, Gishizky M. High affinity anti-TIM-3 and anti-KIR monoclonal antibodies cloned from healthy human individuals. PLoS ONE. 2017;12:e0181464 pubmed publisher
product information
brand :
R&D Systems
master code :
2238-KR
SKU :
2238-KR-050
product name :
Recombinant Human KIR2DL4/CD158d Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Human KIR2DL4/CD158d Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human KIR2DL4/CD158d Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
KIR2DL4/CD158d
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
65 kDa, reducing conditions
theoretical molecular weight :
24.4 kDa (monomer)
gene symbol :
KIR2DL4
details of functionality :
Measured by its ability to inhibit anti-KIR2DL4 antibody induced IFN-gamma secretion by NK-92 human natural killer lymphoma cells. The ED50 for this effect is 0.3-1 ╡g/mL in the presence of 1 ╡g/mL of immobilized mouse anti-hKIR2DL4 antibody (Catalog # MAB2238).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q99706
applications :
Bioactivity
source :
NS0-derived Recombinant Human KIR2DL4/CD158d Fc Chimera Protein, CF
USD :
518 USD
alt names :
103AS, 15.212, CD158 antigen-like family member D, CD158d, CD158d antigen, CD158DKIR103ASKiller cell inhibitory receptor 103AS, G9P, killer cell immunoglobulin-like receptor 2DL4, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4, killer Ig receptor, KIR103, KIR-103AS, MHC class I NK cell receptor KIR103AS, natural killer cell inhibitory receptor, NK cell receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.