Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF | R&D Systems 2237-SE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF

catalog :

2237-SE-010

quantity :

10 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Sima N, Li R, Huang W, Xu M, Beers J, Zou J, et al. Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses. Orphanet J Rare Dis. 2018;13:54 pubmed publisher
Tracy C, Whiting R, Pearce J, Williamson B, Vansteenkiste D, Gillespie L, et al. Intravitreal implantation of TPP1-transduced stem cells delays retinal degeneration in canine CLN2 neuronal ceroid lipofuscinosis. Exp Eye Res. 2016;152:77-87 pubmed publisher

product information

brand :

R&D Systems

master code :

2237-SE

SKU :

2237-SE-010

product name :

Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF

unit size :

10 ug

seo description :

The Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Tripeptidyl-Peptidase I/TPP1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

dilution :

Enzyme Activity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

65-75 kDa, reducing conditions

theoretical molecular weight :

61 kDa

gene symbol :

TPP1

details of functionality :

Measured by the cleavage of Ala-Ala-Phe-AMC. The specific activity is 850 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O14773

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF

USD :

443 USD

alt names :

Cell growth-inhibiting gene 1 protein, ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease), CLN2, CLN2EC 3.4.14.9, growth-inhibiting protein 1, LINCL, LPIC, lysosomal pepstatin insensitive protease, Lysosomal pepstatin-insensitive protease, MGC21297, TPP1, TPP-1, TPP-I, Tripeptidyl aminopeptidase, tripeptidyl peptidase I, tripeptidyl-peptidase 1, Tripeptidyl-peptidase I, TripeptidylPeptidase I

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage