Recombinant Human Galectin-3BP/MAC-2BP Protein, CF | R&D Systems 2226-GAB-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Galectin-3BP/MAC-2BP Protein, CF

catalog :

2226-GAB-050

quantity :

50 ug

price :

514 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Panigrahi A, Benicky J, Aljuhani R, Mukherjee P, Nov xe1 kov xe1 Z, Ba x159 inka C, et al. Galectin-3-binding protein inhibits extracellular heparan 6-O-endosulfatse Sulf-2. bioRxiv. 2023;: pubmed publisher
Seki T, Kanagawa M, Kobayashi K, Kowa H, Yahata N, Maruyama K, et al. Galectin 3-binding protein suppresses amyloid-β production by modulating β-cleavage of amyloid precursor protein. J Biol Chem. 2020;295:3678-3691 pubmed publisher
White M, Roife D, Gomer R. Galectin-3 Binding Protein Secreted by Breast Cancer Cells Inhibits Monocyte-Derived Fibrocyte Differentiation. J Immunol. 2015;195:1858-67 pubmed publisher
Silverman A, Nakata R, Shimada H, Sposto R, DeClerck Y. A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma. Cancer Res. 2012;72:2228-38 pubmed publisher
Fukaya Y, Shimada H, Wang L, Zandi E, DeClerck Y. Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma. J Biol Chem. 2008;283:18573-81 pubmed publisher

product information

brand :

R&D Systems

master code :

2226-GAB

SKU :

2226-GAB-050

product name :

Recombinant Human Galectin-3BP/MAC-2BP Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human Galectin-3BP/MAC-2BP Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Galectin-3BP/MAC-2BP Protein, CF has been validated for the following applications: Bioactivity.

target :

Galectin-3BP/MAC-2BP

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and DTT with Trehalose.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

26-30 kDa, 60-69 kDa and 81-94 kDa, reducing conditions

theoretical molecular weight :

65 kDa

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Galectin-3BP/MAC-2BP is immobilizedat 0.5 ╡g/mL,100 ╡L/well, It can bind Recombinant Human Galectin-3 (Catalog # 1154-GA ) with an ED50 of 0.2-1 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human Galectin-3BP/MAC-2BP Protein Bioactivity

accessionNumbers :

Q08380.1

applications :

Bioactivity

source :

NS0-derived Recombinant Human Galectin-3BP/MAC-2BP Protein, CF

USD :

514 USD

alt names :

90K, Basement membrane autoantigen p105, BTBD17B, galectin-3-binding protein, Galectin3BP, L3 antigen, Lectin galactoside-binding soluble 3-binding protein, lectin, galactoside-binding, soluble, 3 binding protein, LGALS3BP, M2BP, Mac-2 BP, Mac-2-binding protein, MAC2BP, MAC-2BP, MAC-2-BP, serum protein 90K, Tumor-associated antigen 90K

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage