product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse NKp46/NCR1 Fc Chimera Protein, CF
catalog :
2225-NK-050
quantity :
50 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Sen Santara S, Lee D, Crespo x, Hu J, Walker C, Ma X, et al. The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells. Nature. 2023;616:348-356 pubmed publisher
Chinnery F, King C, Elliott T, Bateman A, James E. Viral antigen mediated NKp46 activation of NK cells results in tumor rejection via NK-DC crosstalk. Oncoimmunology. 2012;1:874-883 pubmed
product information
master code :
2225-NK
SKU :
2225-NK-050
product name :
Recombinant Mouse NKp46/NCR1 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse NKp46/NCR1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse NKp46/NCR1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
NKp46/NCR1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
67-77 kDa, reducing conditions
theoretical molecular weight :
53.1 kDa (monomer)
gene symbol :
Ncr1
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Mouse NKp46/NCR1 Fc Chimera is immobilized at 0.5 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human Vimentin (Catalog # 2105-VI ) that produces 50% of the optimal binding response is found to be approximately 30-150 ng/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q8C567
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse NKp46/NCR1 protein Mouse NKp46 (Glu22-Asn255) Accession # Q8C567 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
NS0
USD :
456 USD
alt names :
CD335, CD335 antigen, hNKp46, Ly94, LY94lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46), Lymphocyte antigen 94 homolog, MAR-1, natural cytotoxicity triggering receptor 1, Natural killer cell p46-related protein, NCR1, NK cell-activating receptor, NKp46, NKP46FLJ99094, NK-p46lymphocyte antigen 94 (mouse) homolog (activating NK-receptor; NK-p46)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.