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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-11 Protein
catalog :
218-IL-005
quantity :
5 ug (also 25 ug)
price :
325 USD
more info or order :
citations: 25
Reference |
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Simmons P, Robinson S, Munsell M, Thomas M, Javni J, Brouard N, et al. Expression of a surface antigen (MA6) by peripheral blood CD34+ cells is correlated with improved platelet engraftment and may explain delayed platelet engraftment following cord blood transplantation. Stem Cells Dev. 2015;24:1066-72 pubmed publisher
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Brechter A, Lerner U. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression. Arthritis Rheum. 2007;56:910-23 pubmed
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Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, et al. Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells. Cell Death Differ. 2006;13:1686-96 pubmed
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Mandelin J, Li T, Hukkanen M, Liljeström M, Salo J, Santavirta S, et al. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K. J Rheumatol. 2005;32:713-20 pubmed
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Kao C, Chen Y, Thai P, Wachi S, Huang F, Kim C, et al. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol. 2004;173:3482-91 pubmed
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Van der Meeren A, Mouthon M, Vandamme M, Squiban C, Aigueperse J. Combinations of cytokines promote survival of mice and limit acute radiation damage in concert with amelioration of vascular damage. Radiat Res. 2004;161:549-59 pubmed
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Cork B, Tuckerman E, Li T, Laird S. Expression of interleukin (IL)-11 receptor by the human endometrium in vivo and effects of IL-11, IL-6 and LIF on the production of MMP and cytokines by human endometrial cells in vitro. Mol Hum Reprod. 2002;8:841-8 pubmed
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Manz M, Miyamoto T, Akashi K, Weissman I. Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A. 2002;99:11872-7 pubmed
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Curti A, Ratta M, Corinti S, Girolomoni G, Ricci F, Tazzari P, et al. Interleukin-11 induces Th2 polarization of human CD4(+) T cells. Blood. 2001;97:2758-63 pubmed
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product information
master code :
218-IL
SKU :
218-IL-005
product name :
Recombinant Human IL-11 Protein
unit size :
5 ug (also 25 ug)
description :
The Recombinant Human IL-11 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human IL-11 Protein has been validated for the following applications: Bioactivity.
target :
IL-11
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS and EDTA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
23 kDa, reducing conditions
theoretical molecular weight :
19 kDa
gene symbol :
IL11
details of functionality :
Measured in a cell proliferation assay using T11 mouse plasmacytoma cells. Nordan, R.P. etáal . (1987) J. Immunol. 139 :813. The ED50 for this effect is 0.02-0.12 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P20809.1
applications :
Bioactivity
source long :
Spodoptera frugiperda , Sf 21 (baculovirus)-derived human IL-11 protein Pro22-Leu199
source short :
Sf 21 (baculovirus)
extended description :
Analyzed by SEC-MALS
USD :
325 USD
product details :
Analyzed by SEC-MALS
alt names :
Adipogenesis inhibitory factor, AGIF, AGIFoprelvekin, IL11, IL-11Oprelvekin, interleukin 11, interleukin-11, Oprelvekin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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