Recombinant Mouse Pentraxin 3/TSG-14 Protein | R&D Systems 2166-TS-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Pentraxin 3/TSG-14 Protein

catalog :

2166-TS-025

quantity :

25 ug

price :

456 USD

citations: 6

Reference
Chen F, Wu Y, Cheng C, Hsiao Y, Chi J, Hung L, et al. Inactivation of pentraxin 3 suppresses M2-like macrophage activity and immunosuppression in colon cancer. J Biomed Sci. 2024;31:10 pubmed publisher
Liu M, Deng W, Tang L, Liu M, Bao H, Guo C, et al. Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling. Nat Commun. 2022;13:1006 pubmed publisher
Gupta G, Mou Z, Jia P, Sharma R, Zayats R, Viana S, et al. The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Regulating CD4+ T Helper Cell Response. Cell Rep. 2020;33:108513 pubmed publisher
Zhou C, Chen H, Zheng J, Guo Z, Huang Z, Wu Y, et al. Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice. Neural Regen Res. 2020;15:2318-2326 pubmed publisher
Foo S, Chen W, Taylor A, Sheng K, Yu X, Teng T, et al. Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation. PLoS Pathog. 2015;11:e1004649 pubmed publisher
Rodriguez Grande B, Varghese L, Molina Holgado F, Rajkovic O, Garlanda C, Denes A, et al. Pentraxin 3 mediates neurogenesis and angiogenesis after cerebral ischaemia. J Neuroinflammation. 2015;12:15 pubmed publisher

product information

master code :

2166-TS

SKU :

2166-TS-025

product name :

Recombinant Mouse Pentraxin 3/TSG-14 Protein

unit size :

25 ug

description :

The Recombinant Mouse Pentraxin 3/TSG-14 Protein from R&D Systems is derived from NS0. The Recombinant Mouse Pentraxin 3/TSG-14 Protein has been validated for the following applications: Binding Activity.

target :

Pentraxin 3/TSG-14

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MOPS, NaCl and CaCl2 with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

46 kDa, reducing conditions

theoretical molecular weight :

41 kDa (monomer)

gene symbol :

Ptx3

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rhC1q at 5 ╡g/mL (100 ╡L/well) can bind rmPentraxin 3 with a linear range of 0.25-15 ╡g/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P48759

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse Pentraxin 3/TSG-14 protein Glu18-Ser381, with a C-terminal 6-His tag

source short :

NS0

USD :

456 USD

alt names :

alpha-induced protein 5, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, Pentaxin-related protein PTX3, pentraxin 3, long, pentraxin-3, pentraxin-related gene, rapidly induced by IL-1 beta, pentraxin-related protein PTX3, PTX3, TNF alpha-induced protein 5, TNFAIP5, TSG14, TSG-14, TSG-14pentaxin-related gene, rapidly induced by IL-1 beta, Tumor necrosis factor alpha-induced protein 5, tumor necrosis factor, alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, tumor necrosis factor-inducible protein TSG-14

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.