Recombinant Human M-CSF (CHO-expressed) Protein | R&D Systems 216-MCC-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human M-CSF (CHO-expressed) Protein

catalog :

216-MCC-010

quantity :

10 ug

price :

248 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Cheng Q, Behzadi F, Sen S, Ohta S, Spreafico R, Teles R, et al. Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions. Sci Rep. 2019;9:5288 pubmed publisher
Hayama Y, Kimura T, Takeda Y, Nada S, Koyama S, Takamatsu H, et al. Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB. J Immunol. 2018;200:3790-3800 pubmed publisher

image

image 1 :

Recombinant Human M-CSF (CHO-expressed) Protein Bioactivity

product information

brand :

R&D Systems

master code :

216-MCC

SKU :

216-MCC-010

product name :

Recombinant Human M-CSF (CHO-expressed) Protein

unit size :

10 ug

description :

The Recombinant Human M-CSF (CHO-expressed) Protein, CF from R&D Systems is derived from CHO. The Recombinant Human M-CSF (CHO-expressed) Protein, CF has been validated for the following applications: Bioactivity.

target :

M-CSF

category :

Proteins and Enzymes

alt names :

colony stimulating factor 1 (macrophage), CSF1, CSF-1, Lanimostim, macrophage colony stimulating factor, macrophage colony-stimulating factor 1, MCSF, M-CSF, MCSFlanimostim, MGC31930

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

all available conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

41-50 kDa, reducing conditions

theoretical molecular weight :

25.1 kDa (monomer)

gene symbol :

CSF1

details of functionality :

Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. Nakoinz, I. et al . (1990) J. Immunol. 145 :860. The ED50 for this effect is 0.6-2.4 ng/mL.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P09603

applications :

Bioactivity

source :

CHO-derived Recombinant Human M-CSF (CHO-expressed) Protein

USD :

229

Jul-22 :

248 USD

sizes available :

10 ug

more info or order :

R&D Systems product webpage