Recombinant Human M-CSF GMP Protein, CF | R&D Systems 216-GMP-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human M-CSF GMP Protein, CF

catalog :

216-GMP-025

quantity :

25 ug (also 500 ug)

price :

807 USD

citations: 3

Reference
Anderson A, Parashar K, Jin K, Clor J, Stagnaro C, Vani U, et al. Characterization of AB598, a CD39 Enzymatic Inhibitory Antibody for the Treatment of Solid Tumors. Mol Cancer Ther. 2024;23:1471-1482 pubmed publisher
Bolis M, Bossi D, Vallerga A, Ceserani V, Cavalli M, Impellizzieri D, et al. Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression. Nat Commun. 2021;12:7033 pubmed publisher
Fraser A, Pass C, Burgoyne P, Atkinson A, Bailey L, Laurie A, et al. Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis. Cytotherapy. 2017;19:1113-1124 pubmed publisher

product information

master code :

216-GMP

SKU :

216-GMP-025

product name :

Recombinant Human M-CSF GMP Protein, CF

unit size :

25 ug (also 500 ug)

description :

The Recombinant Human M-CSF GMP Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human M-CSF GMP Protein, CF has been validated for the following applications: Bioactivity.

target :

M-CSF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

species :

Human

observed molecular weight :

37 kDa, non-reducing conditions

theoretical molecular weight :

18.5 kDa (monomer)

gene symbol :

CSF1

details of functionality :

Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. Nakoinz, I. et al . (1990) J. Immunol. 145 :860. The ED50 for this effect is 0.5-1.5 ng/mL. The specific activity of Recombinant Human M-CSF is 6.0 x 107 IU/mg, which is calibrated against the human M-CSF WHO International Standard (NIBSC code: 89/512).

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human M-CSF GMP Protein Bioactivity

accessionNumbers :

NP_757350.2

applications :

Bioactivity

source long :

E. coli -derived human M-CSF protein Glu33-Ser190, with an N-terminal Met Produced using non-animal reagents in an animal-free laboratory. Manufactured and tested under cGMP guidelines.

source short :

E. coli

extended description :

Animal-Free.

USD :

807 USD

product details :

Animal-Free.

alt names :

colony stimulating factor 1 (macrophage), CSF1, CSF-1, Lanimostim, macrophage colony stimulating factor, macrophage colony-stimulating factor 1, MCSF, M-CSF, MCSFlanimostim, MGC31930

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at <= -20 ░C as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.