Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF | R&D Systems 2159-FA-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF

catalog :

2159-FA-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Mahmoud A, Galdos F, Dinan K, Jedrychowski M, Davis J, Vujic A, et al. Apolipoprotein E is a pancreatic extracellular factor that maintains mature β-cell gene expression. PLoS ONE. 2018;13:e0204595 pubmed publisher
Waetzig V, Loose K, Haeusgen W, Herdegen T. c-Jun N-terminal kinases mediate Fas-induced neurite regeneration in PC12 cells. Biochem Pharmacol. 2008;76:1476-84 pubmed publisher
Liu Y, Zhang X. Murine coronavirus-induced oligodendrocyte apoptosis is mediated through the activation of the Fas signaling pathway. Virology. 2007;360:364-75 pubmed

product information

master code :

2159-FA

SKU :

2159-FA-050

product name :

Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Fas/TNFRSF6/CD95

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

observed molecular weight :

60-65 kDa, reducing conditions

theoretical molecular weight :

43.3 kDa (monomer)

gene symbol :

Fas

details of functionality :

Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. Cheng, J. etáal . (1994) Science 263 :1759. The ED50 for this effect is 0.05-0.25 ╡g/mL in the presence of 100 ng/mL recombinant rat Fas Ligand.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_631933

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived rat Fas/TNFRSF6/CD95 protein Rat Fas (Gln22 - Lys170) Accession # NP_631933 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

Apo-1, Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1, APT1FASTM, CD95, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage