Recombinant Mouse B7-H4 His-tag Protein, CF | R&D Systems 2154-B7-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse B7-H4 His-tag Protein, CF

catalog :

2154-B7-050

quantity :

50 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Radichev I, Maneva Radicheva L, Amatya C, Parker C, Ellefson J, Wasserfall C, et al. Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development. Diabetes. 2014;63:3470-82 pubmed publisher
Chen X, Quinn E, Ni H, Wang J, Blankson S, Redmond H, et al. B7-H3 participates in the development of experimental pneumococcal meningitis by augmentation of the inflammatory response via a TLR2-dependent mechanism. J Immunol. 2012;189:347-55 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2154-B7

SKU :

2154-B7-050

product name :

Recombinant Mouse B7-H4 His-tag Protein, CF

Description :

The Recombinant Mouse B7-H4 His-tag Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse B7-H4 His-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

B7-H4

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

45-55 kDa, reducing conditions

theoretical molecular weight :

26.6 kDa

gene symbol :

Vtcn1

details of functionality :

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The presence of Recombinant Mouse B7-H4 at 10 µg/mL inhibited the anti-CD3 response by 30%. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q7TSP5

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse B7-H4 His-tag Protein

USD :

423 USD

alt names :

B7h.5, B7H4, B7-H4, B7H4T-cell costimulatory molecule B7x, B7S1, B7S1VCTN1, B7x, B7XPRO1291, FLJ22418, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, V-set domain containing T cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage