This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Siglec-10 Fc Chimera Protein, CF
catalog :
2130-SL
quantity :
50 ug
price :
359 USD
citations: 3
Reference
Terävä J, Tiainen L, Lamminmaki U, Kellokumpu Lehtinen P, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma. PLoS ONE. 2019;14:e0219480 pubmed publisher
Chen G, Brown N, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. elife. 2014;3:e04066 pubmed publisher
Chen G, Chen X, King S, Cavassani K, Cheng J, Zheng X, et al. Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction. Nat Biotechnol. 2011;29:428-35 pubmed publisher
product information
brand :
R&D Systems
master code :
2130-SL
SKU :
2130-SL-050
product name :
Recombinant Human Siglec-10 Fc Chimera Protein, CF
description :
The Recombinant Human Siglec-10 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Siglec-10 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
Siglec-10
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
105-110 kDa, reducing conditions
theoretical molecular weight :
85 kDa (monomer)
gene symbol :
SIGLEC10
details of functionality :
Measured by its ability to bind biotinylated 6’-Sialyllactose-Polyacrylamide in functional ELISA. Whitney, G. et al . (2001) FEBS 268 :6083. rhSiglec-10/Fc Chimera immobilized at 5 µg/mL (100 µL/well) on a goat anti-human IgG Fc antibody (Catalog # G-102-C) coated plate can bind biotinylated 6’-Sialyllactose-Polyacrylamide with a linear range of 0.04-2.5 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
2130-SL
accessionNumbers :
Q96LC7
applications :
Binding Activity
source :
Mouse myeloma cell line, NS0-derived human Siglec-10 protein Human Siglec-10 (Met17-Thr546) Accession # Q96LC7 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
2020 USD :
359
2021 USD :
359 USD
alt names :
MGC126774, PRO940, sialic acid binding Ig-like lectin 10, sialic acid-binding Ig-like lectin 10, Siglec10, SIGLEC-10, siglec-like gene 2, Siglec-like protein 2, SLG2, SLG2sialic acid binding Ig-like lectin 10 Ig-like lectin 7
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.