Recombinant Human Siglec-10 Fc Chimera Protein, CF | R&D Systems 2130-SL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Siglec-10 Fc Chimera Protein, CF

catalog :

2130-SL-050

quantity :

50 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Terävä J, Tiainen L, Lamminmaki U, Kellokumpu Lehtinen P, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma. PLoS ONE. 2019;14:e0219480 pubmed publisher
Chen G, Brown N, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. elife. 2014;3:e04066 pubmed publisher
Chen G, Chen X, King S, Cavassani K, Cheng J, Zheng X, et al. Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction. Nat Biotechnol. 2011;29:428-35 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2130-SL

SKU :

2130-SL-050

product name :

Recombinant Human Siglec-10 Fc Chimera Protein, CF

Description :

The Recombinant Human Siglec-10 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Siglec-10 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

Siglec-10

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

105-110 kDa, reducing conditions

theoretical molecular weight :

85 kDa (monomer)

gene symbol :

SIGLEC10

details of functionality :

Measured by its ability to bind biotinylated 6’-Sialyllactose-Polyacrylamide in functional ELISA. Whitney, G. et al . (2001) FEBS 268 :6083. rhSiglec-10/Fc Chimera immobilized at 5 µg/mL (100 µL/well) on a goat anti-human IgG Fc antibody (Catalog # G-102-C) coated plate can bind biotinylated 6’-Sialyllactose-Polyacrylamide with a linear range of 0.04-2.5 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q96LC7

applications :

Binding Activity

source :

NS0-derived Recombinant Human Siglec-10 Fc Chimera Protein

USD :

447 USD

alt names :

MGC126774, PRO940, sialic acid binding Ig-like lectin 10, sialic acid-binding Ig-like lectin 10, Siglec10, SIGLEC-10, siglec-like gene 2, Siglec-like protein 2, SLG2, SLG2sialic acid binding Ig-like lectin 10 Ig-like lectin 7

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage