This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
other
product name :
Recombinant Human GDNF Protein
catalog :
212-GD-010
quantity :
10 ug (also 50 ug, 1 mg)
price :
309 USD
product information
brand :
R&D Systems
master code :
212-GD
SKU :
212-GD-010
product name :
Recombinant Human GDNF Protein
description :
The Recombinant Human GDNF Protein from R&D Systems is derived from NS0. The Recombinant Human GDNF Protein has been validated for the following applications: Bioactivity, Binding Activity.
target :
GDNF
category :
Proteins and Enzymes
unit size :
10 ug (also 50 ug, 1 mg)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
11.6 kDa (monomer)
gene symbol :
GDNF
details of functionality :
Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFR alpha-1/GDNF R alpha-1 Fc Chimera (Catalog # 714-GR ). The specific activity of recombinant human GDNF is approximately 3.1 x 103 units/µg, which is calibrated against recombinant human GDNF Reference Standard (NIBSC code: 09/266). Specific activity is for reference purposes only and is not routinely tested. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFR alpha-1/GDNF R alpha-1 Fc Chimera (Catalog # 714-GR ) at 1 µg/mL can bind Recombinant Human GDNF with an apparent Kd 1 nM.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P39905
applications :
Bioactivity, Binding Activity
source :
The Recombinant Human GDNF Protein from R&D Systems is derived from Mouse myeloma cell line, NS0-derived human GDNF protein Arg109-Ile211. The Recombinant Human GDNF Protein has been validated for the following applications: Bioactivity, Binding Activity.
USD 2021 :
299
USD 2022 :
309 USD
alt name :
Astrocyte-derived trophic factor, ATF, ATF1, ATF2, glial cell derived neurotrophic factor, glial cell line derived neurotrophic factor, glial cell line-derived neurotrophic factor, HFB1-GDNF, HGDNF, HSCR3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.