Human IFN-alpha Antibody | R&D Systems 21112-1 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IFN-alpha Antibody

catalog :

21112-1

quantity :

50 ug

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MMHA-11

reactivity :

human

application :

ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 3

Reference
Bin L, Li X, Richers B, Streib J, Hu J, Taylor P, et al. Ankyrin repeat domain 1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum. J Allergy Clin Immunol. 2018;141:2085-2093.e1 pubmed publisher
Richez C, Yasuda K, Watkins A, Akira S, Lafyatis R, VAN SEVENTER J, et al. TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming. J Immunol. 2009;182:820-8 pubmed
Lee P, Li Y, Richards H, Chan F, Zhuang H, Narain S, et al. Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus. Arthritis Rheum. 2007;56:3759-69 pubmed

product information

master code :

21112-1

SKU :

21112-1

product name :

Human IFN-alpha Antibody

unit size :

50 ug

description :

The Human IFN-alpha Antibody from R&D Systems is a mouse monoclonal antibody to IFN-alpha. This antibody reacts with human,mouse. The Human IFN-alpha Antibody has been validated for the following applications: ELISA Development,Neutralization,ELISA.

target :

IFN-alpha

category :

Primary Antibodies

buffer :

Phosphate-buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)

clonality :

Monoclonal

clone :

MMHA-11

conjugate :

Unconjugated

host :

Mouse

immunogen :

Human Leukocyte Interferon

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

One neutralization unit is the amount of antiserum required to neutralize one unit of human interferon alpha (Hu-IFN-alpha ) to a 50% endpoint. Interferon was titrated with the use of the cytopathic effect inhibition assay as described [Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol . 37, 755-758; Familletti, P.C., Rubinstein, S., and Pestka, S. (1981) "A Convenient and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology, Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394]. In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%. The units are determined with respect to the international reference standard for Hu-IFN-alpha provided by the National Institutes of Health [see Pestka, S. (1986) "Interferon Standards and General Abbreviations," in Methods in Enzymology (S. Pestka, ed.), Academic Press, New York 119, 14-23].

gene symbol :

IFNA2

endotoxin note :

<1.0 EU per 1 ╡g of the antibody by the LAL method.

applications :

ELISA Development,Neutralization,ELISA

USD :

399 USD

alt names :

IFNA, IFNA2, IFNA2b, IFNalpha, IFN-alphaA, INFA2, interferon alpha 2, LeIF D

storage :

After receipt, the product may be stored at -20░C for short-term use ( <= 6 months). For long-term storage, we recommend storing the product at -70░C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

more info or order :

R&D Systems product webpage