product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Vimentin Protein, CF
catalog :
2105-VI-100
quantity :
100 ug
price :
423 USD
more info or order :
citations: 7
Reference
Umemoto A, Kuwada T, Murata K, Shiokawa M, Ota S, Murotani Y, et al. Identification of anti-citrullinated osteopontin antibodies and increased inflammatory response by enhancement of osteopontin binding to fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Res Ther. 2023;25:25 pubmed publisher
Sugawara E, Kato M, Kudo Y, Lee W, Hisada R, Fujieda Y, et al. Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts. Autophagy. 2020;16:946-955 pubmed publisher
Satelli A, Hu J, Xia X, Li S. Potential Function of Exogenous Vimentin on the Activation of Wnt Signaling Pathway in Cancer Cells. J Cancer. 2016;7:1824-1832 pubmed
Bidkar M, Vassallo R, Luckey D, Smart M, Mouapi K, Taneja V. Cigarette Smoke Induces Immune Responses to Vimentin in both, Arthritis-Susceptible and -Resistant Humanized Mice. PLoS ONE. 2016;11:e0162341 pubmed publisher
Conti F, Capozzi A, Truglia S, Lococo E, Longo A, Misasi R, et al. The mosaic of "seronegative" antiphospholipid syndrome. J Immunol Res. 2014;2014:389601 pubmed publisher
Satelli A, Mitra A, Cutrera J, Devarie M, Xia X, Ingram D, et al. Universal marker and detection tool for human sarcoma circulating tumor cells. Cancer Res. 2014;74:1645-50 pubmed publisher
Ortona E, Capozzi A, Colasanti T, Conti F, Alessandri C, Longo A, et al. Vimentin/cardiolipin complex as a new antigenic target of the antiphospholipid syndrome. Blood. 2010;116:2960-7 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
2105-VI
SKU :
2105-VI-100
product name :
Recombinant Human Vimentin Protein, CF
Description :
The Recombinant Human Vimentin Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Vimentin Protein, CF has been validated for the following applications: Binding Activity.
target :
Vimentin
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with Trehalose.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
theoretical molecular weight :
54.4 kDa
gene symbol :
VIM
details of functionality :
Measured by its ability to bind Recombinant Human NKp46/NCR1 Fc Chimera (Catalog # 1850-NK ) in a functional ELISA with an estimated KD   2 nM. Garg, A. et al . (2006) J. Immunol. 177 :6192.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P08670
applications :
Binding Activity
source :
E. coli-derived Recombinant Human Vimentin Protein
USD :
423 USD
alt names :
epididymis secretory sperm binding protein, FLJ36605, VIM, vimentin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.