Recombinant Human IL-9 Protein, CF | R&D Systems 209-ILB-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-9 Protein, CF

catalog :

209-ILB-010/CF

quantity :

10 ug (also 50 ug)

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 10

Reference
Pavlidis P, Tsakmaki A, Treveil A, Li K, Cozzetto D, Yang F, et al. Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease. Cell Rep. 2022;40:111439 pubmed publisher
Peng Z, Jiang S, Wu M, Zhou X, Wang Q. Expression and role of interleukin-9 in Vogt-Koyanagi-Harada disease. Mol Vis. 2017;23:538-547 pubmed
Ding J, Fishel M, Reed A, McAdams E, CZADER M, Cardoso A, et al. Ref-1/APE1 as a Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia. Mol Cancer Ther. 2017;16:1401-1411 pubmed publisher
Liu J, Harberts E, Tammaro A, Girardi N, Filler R, Fishelevich R, et al. IL-9 regulates allergen-specific Th1 responses in allergic contact dermatitis. J Invest Dermatol. 2014;134:1903-1911 pubmed publisher
Zhang J, Shan L, Koussih L, Redhu N, Halayko A, Chakir J, et al. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production. PLoS ONE. 2012;7:e34965 pubmed publisher
Nielsen N, Ødum N, Ursø B, Lanier L, Spee P. Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A. PLoS ONE. 2012;7:e31959 pubmed publisher
Qiu L, Lai R, Lin Q, Lau E, Thomazy D, Calame D, et al. Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells. Blood. 2006;108:2407-15 pubmed
Fujitsu Y, Fukuda K, Kimura K, Seki K, Kumagai N, Nishida T. Protection of human conjunctival fibroblasts from NO-induced apoptosis by interleukin-4 or interleukin-13. Invest Ophthalmol Vis Sci. 2005;46:797-802 pubmed
Kao C, Chen Y, Thai P, Wachi S, Huang F, Kim C, et al. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol. 2004;173:3482-91 pubmed
Vermeer P, Harson R, Einwalter L, Moninger T, Zabner J. Interleukin-9 induces goblet cell hyperplasia during repair of human airway epithelia. Am J Respir Cell Mol Biol. 2003;28:286-95 pubmed

image

image 1 :

Recombinant Human IL-9 Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

209-ILB/CF

SKU :

209-ILB-010/CF

product name :

Recombinant Human IL-9 Protein, CF

Description :

The Recombinant Human IL-9 Protein, CF from R&D Systems is derived from Sf 21 (stably transfected). The Recombinant Human IL-9 Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-9

category :

Proteins and Enzymes

unit size :

10 ug (also 50 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

12-24 kDa, reducing conditions

theoretical molecular weight :

14 kDa

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=proteinsandenzymes

details of functionality :

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Avanzi, G. et al . (1988) Br. J. Haematol. 69 :359. The ED50 for this effect is 0.03-0.3 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P15248

applications :

Bioactivity

source :

Sf 21 (stably transfected)-derived Recombinant Human IL-9 Protein

USD :

396 USD

alt names :

Cytokine P40, HP40, IL9, IL-9homolog of mouse T cell and mast cell growth factor 40, interleukin 9, interleukin-9, P40, p40 cytokine, p40 T-cell and mast cell growth factor, T-cell growth factor P40

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage