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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Langerin/CD207 Protein, CF
catalog :
2088-LN-050
quantity :
50 ug
price :
432 USD
more info or order :
citations: 2
Reference
Gao C, Stavenhagen K, Eckmair B, McKitrick T, Mehta A, Matsumoto Y, et al. Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity. Sci Adv. 2021;7: pubmed publisher
van den Berg L, Cardinaud S, van der Aar A, Sprokholt J, de Jong M, Zijlstra Willems E, et al. Langerhans Cell-Dendritic Cell Cross-Talk via Langerin and Hyaluronic Acid Mediates Antigen Transfer and Cross-Presentation of HIV-1. J Immunol. 2015;195:1763-73 pubmed publisher
product information
master code :
2088-LN
SKU :
2088-LN-050
product name :
Recombinant Human Langerin/CD207 Protein, CF
unit size :
50 ug
description :
The Recombinant Human Langerin/CD207 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Langerin/CD207 Protein, CF has been validated for the following applications: Binding Activity.
target :
Langerin/CD207
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
35-40 kDa, reducing conditions
theoretical molecular weight :
31 kDa
gene symbol :
CD207
details of functionality :
Measured by its ability to bind biotinylated Mannose-Polyacrylamide in a functional ELISA. Valladeau, J. et al . (2000) Immunity 12 :71.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q9UJ71
applications :
Binding Activity
source long :
Mouse myeloma cell line, NS0-derived human Langerin/CD207 protein Tyr64-Pro328, with an N-terminal 9-His tag
source short :
NS0
extended description :
His-tag
USD :
432 USD
product details :
His-tag
alt names :
CD207, CD207 antigen, CD207 antigen, langerin, CD207 molecule, langerin, CLEC4KLangerhans cell specific c-type lectin, C-type lectin domain family 4 member K, C-type lectin domain family 4, member K, Langerin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.