product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Semaphorin 7A Fc Chimera Protein, CF
catalog :
2068-S7-050
quantity :
50 ug
price :
491 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Huang J, Zhao C, Zhang S. Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease. BMC Pediatr. 2024;24:285 pubmed publisher
Manini I, Ruaro M, Sgarra R, Bartolini A, Caponnetto F, Ius T, et al. Semaphorin-7A on Exosomes: A Promigratory Signal in the Glioma Microenvironment. Cancers (Basel). 2019;11: pubmed publisher
Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
Roth J, Köhler D, Schneider M, Granja T, Rosenberger P. Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury. PLoS ONE. 2016;11:e0146930 pubmed publisher
product information
master code :
2068-S7
SKU :
2068-S7-050
product name :
Recombinant Human Semaphorin 7A Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human Semaphorin 7A Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Semaphorin 7A Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Semaphorin 7A
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
100-105 kDa, reducing conditions
theoretical molecular weight :
94.8 kDa (monomer)
gene symbol :
SEMA7A
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Plexin C1 (Catalog # 3887-PC ) is coated at 5 ╡g/mL, Recombinant Human Semaphorin 7A Fc Chimera binds with an apparent Kd 5 nM.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
O75326
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human Semaphorin 7A protein Human Semaphorin 7A (His47-Ala648) Accession # O75326 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
NS0
USD :
491 USD
alt names :
CD108, CD108 antigen, CD108MGC126696, CDw108, H-SEMA-K1, H-Sema-L, JMH, JMH blood group antigen, John-Milton-Hargen human blood group Ag, MGC126692, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin)7A, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin)7A (JMH blood group), sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A, Sema K1, Sema L, Sema7A, SEMAK1, SEMAL, SEMALJohn Milton Hagen blood group H-Sema K1, semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group), semaphorin K1, semaphorin L, semaphorin-7A, semaphorin-K1, Semaphorin-L
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.