Recombinant Human Complement Component C1s Protein, CF | R&D Systems 2060-SE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Complement Component C1s Protein, CF

catalog :

2060-SE-010

quantity :

10 ug

price :

458 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Tang X, Arora G, Matias J, HART T, Cui Y, Fikrig E. A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ. Cell Rep. 2022;41:111673 pubmed publisher
Zhou Z, Chen T, Arora K, Hyams K, Kozlowski S. Complement C1 esterase inhibitor levels linked to infections and contaminated heparin-associated adverse events. PLoS ONE. 2012;7:e34978 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2060-SE

SKU :

2060-SE-010

product name :

Recombinant Human Complement Component C1s Protein, CF

Description :

The Recombinant Human Complement Component C1s Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Complement Component C1s Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Complement Component C1s

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in Tris, NaCl, CaCl2 and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

62 kDa and 32 kDa, reducing conditions

theoretical molecular weight :

47 kDa (A chain) 28 kDa (B chain)

gene symbol :

C1S

details of functionality :

Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Lys-ThioBenzyl ester (Z-Lys-SBzl), in the presence of 5,5’Dithio-bis (2-nitrobenzoic acid) (DTNB). Edwards, K.M. et al . (1999) J. Biol. Chem. 274 :30468. The specific activity is 20,000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P09871

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Complement Component C1s Protein

USD :

458 USD

alt names :

basic proline-rich peptide IB-1, C1 esterase, C1S, complement C1s subcomponent, Complement component 1 subcomponent s, complement component 1, s subcomponent, EC 3.4.21, EC 3.4.21.42, FLJ44757

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage