Recombinant Mouse Legumain/Asparaginyl Endopeptidase, CF | R&D Systems 2058-CY-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Legumain/Asparaginyl Endopeptidase, CF

catalog :

2058-CY-010

quantity :

10 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Lustenberger S, Castro Jaramillo C, B xe4 rtschi L, Williams R, Schibli R, Mu L, et al. Towards imaging the immune state of cancer by PET: Targeting legumain with 11C-labeled P1-Asn peptidomimetics carrying a cyano-warhead. Nucl Med Biol. 2024;138-139:108951 pubmed publisher
Cheng Q, Ma X, Liu J, Feng X, Liu Y, Wang Y, et al. Pharmacological Inhibition of the Asparaginyl Endopeptidase (AEP) in an Alzheimer's Disease Model Improves the Survival and Efficacy of Transplanted Neural Stem Cells. Int J Mol Sci. 2023;24: pubmed publisher

product information

master code :

2058-CY

SKU :

2058-CY-010

product name :

Recombinant Mouse Legumain/Asparaginyl Endopeptidase, CF

unit size :

10 ug

description :

The Recombinant Mouse Legumain/Asparaginyl Endopeptidase, CF from R&D Systems is derived from NS0. The Recombinant Mouse Legumain/Asparaginyl Endopeptidase, CF has been validated for the following applications: Enzyme Activity.

target :

Legumain/Asparaginyl Endopeptidase

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

61 kDa, reducing conditions

theoretical molecular weight :

49 kDa

gene symbol :

Lgmn

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, N-carbobenzyloxy-Ala-Ala-Asn-7-amido-4-methylcoumarin (Z-AAN-AMC). The specific activity is 350 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O89017

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived mouse Legumain/Asparaginyl Endopeptidase protein Val18-Tyr435, with an N-terminal 7-His tag

source short :

NS0

USD :

456 USD

alt names :

AEP, Asparaginyl endopeptidase, cysteine protease 1, legumain, LGMN, LGMN1, Protease, cysteine 1, protease, cysteine, 1 (legumain), PRSC1EC 3.4.22.34

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage