Recombinant Mouse IL-17F Protein, CF | R&D Systems 2057-IL-025/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-17F Protein, CF

catalog :

2057-IL-025/CF

quantity :

25 ug

price :

432 USD

citations: 8

Reference
Katsura H, Kobayashi Y, Tata P, Hogan B. IL-1 and TNFα Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration. Stem Cell Reports. 2019;12:657-666 pubmed publisher
Tang C, Kakuta S, Shimizu K, Kadoki M, Kamiya T, Shimazu T, et al. Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota. Nat Immunol. 2018;19:755-765 pubmed publisher
Nam D, Mau E, Wang Y, Wright D, Silkstone D, Whetstone H, et al. T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair. PLoS ONE. 2012;7:e40044 pubmed publisher
Wilson R, Whitehead G, Nakano H, Free M, Kolls J, Cook D. Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness. Am J Respir Crit Care Med. 2009;180:720-30 pubmed publisher
Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, et al. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity. 2009;30:108-19 pubmed publisher
Nagata T, McKinley L, Peschon J, Alcorn J, Aujla S, Kolls J. Requirement of IL-17RA in Con A induced hepatitis and negative regulation of IL-17 production in mouse T cells. J Immunol. 2008;181:7473-9 pubmed
Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, et al. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis. J Invest Dermatol. 2009;129:650-6 pubmed publisher
Rickel E, Siegel L, Yoon B, Rottman J, Kugler D, Swart D, et al. Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J Immunol. 2008;181:4299-310 pubmed

product information

master code :

2057-IL/CF

SKU :

2057-IL-025/CF

product name :

Recombinant Mouse IL-17F Protein, CF

unit size :

25 ug

description :

The Recombinant Mouse IL-17F Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse IL-17F Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-17F

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

16 kDa, reducing conditions

theoretical molecular weight :

15 kDa (monomer)

gene symbol :

Il17f

details of functionality :

Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. Yao, Z. et al . (1995) Immunity 3 :811. The ED50 for this effect is 20-120 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAM77568

applications :

Bioactivity

source long :

E. coli -derived mouse IL-17F protein Arg21-Ala153, with an N-terminal Met

source short :

E. coli

USD :

432 USD

alt names :

Cytokine ML-1, IL17F, IL-17Finterleukin-17F, interleukin 17F

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.