product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-3 Protein
catalog :
203-IL-010
quantity :
10 ug (also 50 ug, 100 ug, 250 ug, 500 ug, 1 mg)
price :
205 USD
more info or order :
citations: 174
Reference
Michaels Y, Edgar J, Major M, Castle E, Zimmerman C, Yin T, et al. DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells. Sci Adv. 2022;8:eabn5522 pubmed publisher
Liu L, Vujovic A, Deshpande N, Sathe S, Anande G, Chen H, et al. The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors. Nat Commun. 2022;13:3833 pubmed publisher
Lian Q, Zhang K, Zhang Z, Duan F, Guo L, Luo W, et al. Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model. Nat Commun. 2022;13:2028 pubmed publisher
Liu Y, Jia Y, Lv J, Sun D, Yin Y, Liu N, et al. Generation of an induced pluripotent stem cell (iPSC) line from a diabetic patient with glucagon receptor (GCGR) p.W83X mutation. Stem Cell Res. 2022;61:102745 pubmed publisher
Jacobsen A, Pierotti C, Lowes K, Au A, Zhang Y, Etemadi N, et al. The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL. Cell Death Dis. 2022;13:291 pubmed publisher
Dong Y, Li X, Fu W, Tian X, Guo G, Peng Y, et al. Generation of an iPSC line (ZZUNEUi021-A) from a hypertrophic cardiomyopathy patient with TNNT2 mutation. Stem Cell Res. 2022;58:102622 pubmed publisher
Iannello G, Patel A, Sirabella D, Corneo B, Thaker V. Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL. Stem Cell Res. 2021;59:102635 pubmed publisher
de Souza A, Bressan F, Pieri N, Botigelli R, Revay T, Haddad S, et al. Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients. Cells. 2021;10: pubmed publisher
Tipgomut C, Khuhapinant A, Wilson M, Poldee S, Heesom K, Metheetrairut C, et al. MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera. Sci Rep. 2021;11:22483 pubmed publisher
Schwartz G, Kubo H, Laronda M. Generation of two human induced pluripotent stem cell lines from a patient with complete androgen insensitivity syndrome with a hemizygous single nucleotide variant in the androgen receptor (AR) gene. Stem Cell Res. 2021;55:102441 pubmed publisher
Iannello G, Patel A, Sirabella D, Corneo B, Thaker V. Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity. Stem Cell Res. 2021;54:102432 pubmed publisher
Simón Serrano S, Tavecchio M, Grönberg A, Sime W, Jemaà M, Moss S, et al. Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma. Cancers (Basel). 2021;13: pubmed publisher
Newby G, Yen J, Woodard K, Mayuranathan T, Lazzarotto C, Li Y, et al. Base editing of haematopoietic stem cells rescues sickle cell disease in mice. Nature. 2021;595:295-302 pubmed publisher
Borsoi J, Morato Marques M, de Araújo Tofoli F, Assis Pereira L, Farinha Arcieri L, Delgado Sarafian R, et al. Generation of two human induced pluripotent stem cell (hiPSC) lines derived from unrelated Marfan Syndrome patients. Stem Cell Res. 2021;54:102407 pubmed publisher
Matsuo S, Nishinaka Arai Y, Kazuki Y, Oshimura M, Nakahata T, Niwa A, et al. Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification. PLoS ONE. 2021;16:e0247595 pubmed publisher
Jung S, Appleton E, Ali M, Church G, del Sol A. A computer-guided design tool to increase the efficiency of cellular conversions. Nat Commun. 2021;12:1659 pubmed publisher
Kennedy A, Myers K, Bowman J, Gibson C, Camarda N, Furutani E, et al. Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. Nat Commun. 2021;12:1334 pubmed publisher
Wang T, Pine A, Kotini A, Yuan H, Zamparo L, Starczynowski D, et al. Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets. Cell Stem Cell. 2021;28:1074-1089.e7 pubmed publisher
González Menéndez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, et al. An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism. Cell Rep. 2021;34:108723 pubmed publisher
Chen S, Yang L, Nilsson Payant B, Han Y, Jaffré F, Zhu J, et al. SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2. Res Sq. 2020;: pubmed publisher
Trakarnsanga K, Tipgomut C, Metheetrairut C, Wattanapanitch M, Khuhapinant A, Poldee S, et al. Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/β-thalassemia patient. Sci Rep. 2020;10:16798 pubmed publisher
Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed publisher
Duan F, Guo L, Yang L, Han Y, Thakur A, Nilsson Payant B, et al. Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2. Res Sq. 2020;: pubmed publisher
Riccetti S, Sinigaglia A, Desole G, Nowotny N, Trevisan M, Barzon L. Modelling West Nile Virus and Usutu Virus Pathogenicity in Human Neural Stem Cells. Viruses. 2020;12: pubmed publisher
Krishna B, Wass A, O Connor C. Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency. Proc Natl Acad Sci U S A. 2020;117:20860-20867 pubmed publisher
Thornton N, Karamatic Crew V, Tilley L, Green C, Tay C, Griffiths R, et al. Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype. Nat Commun. 2020;11:3569 pubmed publisher
Norden P, Sun Z, Davis G. Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles. PLoS ONE. 2020;15:e0235116 pubmed publisher
Xiao X, Liu P, Li D, Xia Z, Wang P, Zhang X, et al. Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition. J Hematol Oncol. 2020;13:80 pubmed publisher
Wesely J, Kotini A, Izzo F, Luo H, Yuan H, Sun J, et al. Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells. Cell Rep. 2020;31:107688 pubmed publisher
Meinders M, Shoemark D, Dobbe J, Streekstra G, Frayne J, Toye A. Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE. Mol Ther Methods Clin Dev. 2020;17:822-830 pubmed publisher
Rab M, van Oirschot B, Kosinski P, Hixon J, Johnson K, Chubukov V, et al. AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes. Haematologica. 2020;: pubmed publisher
Lemke Miltner C, Blackwell S, Yin C, Krug A, Morris A, Krieg A, et al. Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization. J Immunol. 2020;204:1386-1394 pubmed publisher
Stefka A, Johnson D, Rosebeck S, Park J, Nakamura Y, Jakubowiak A. Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models. Cancer Med. 2020;9:324-334 pubmed publisher
Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
Balaji Ragunathrao V, Anwar M, Akhter M, Chavez A, Mao D, Natarajan V, et al. Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling. Cell Rep. 2019;29:3472-3487.e4 pubmed publisher
Ruiz J, Chen G, Haro Mora J, Keyvanfar K, Liu C, Zou J, et al. Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system. Stem Cell Res. 2019;41:101600 pubmed publisher
Grajcarek J, Monlong J, Nishinaka Arai Y, Nakamura M, Nagai M, Matsuo S, et al. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nat Commun. 2019;10:4856 pubmed publisher
Proto W, Siegel S, Dankwa S, Liu W, Kemp A, Marsden S, et al. Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand. Nat Commun. 2019;10:4512 pubmed publisher
Uchida N, Hsieh M, Raines L, Haro Mora J, Demirci S, Bonifacino A, et al. Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders. Nat Commun. 2019;10:4479 pubmed publisher
Ly M, Rentas S, Vujovic A, Wong N, Moreira S, Xu J, et al. Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance. Cancer Res. 2019;79:5799-5811 pubmed publisher
McKenzie M, Ghisi M, Oxley E, Ngo S, Cimmino L, Esnault C, et al. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. Cell Stem Cell. 2019;25:258-272.e9 pubmed publisher
Nasri M, Ritter M, Mir P, Dannenmann B, Aghaallaei N, Amend D, et al. CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients. Haematologica. 2019;: pubmed publisher
Chang Y, Wang Z, Igawa S, Choi J, Werbel T, Di Nardo A. Lipocalin 2: A New Antimicrobial in Mast Cells. Int J Mol Sci. 2019;20: pubmed publisher
Ruiz Gutierrez M, Bölükbaşı Ö, Alexe G, Kotini A, Ballotti K, Joyce C, et al. Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells. JCI Insight. 2019;5: pubmed publisher
Trakarnsanga K, Ferguson D, Daniels D, Griffiths R, Wilson M, Mordue K, et al. Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation. Stem Cell Res Ther. 2019;10:130 pubmed publisher
Mair B, Tomic J, Masud S, Tonge P, Weiss A, Usaj M, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 2019;27:599-615.e12 pubmed publisher
Seneviratne A, Xu M, Henao J, Fajardo V, Hao Z, Voisin V, et al. The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids. Cell Stem Cell. 2019;24:621-636.e16 pubmed publisher
Xu H, Wang B, Ono M, Kagita A, Fujii K, Sasakawa N, et al. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility. Cell Stem Cell. 2019;: pubmed publisher
Suga M, Kondo T, Imamura K, Shibukawa R, Okanishi Y, Sagara Y, et al. Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I. Stem Cell Res. 2019;36:101406 pubmed publisher
Taylor S, Hogwood J, Guo W, Yates E, Turnbull J. By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans. Sci Rep. 2019;9:2679 pubmed publisher
Vangeti S, Gertow J, Yu M, Liu S, Baharom F, Scholz S, et al. Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection. J Immunol. 2019;202:2069-2081 pubmed publisher
Potirat P, Wattanapanitch M, Viprakasit V, Kheolamai P, Issaragrisil S. An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling. Stem Cell Res. 2019;34:101344 pubmed publisher
Poldee S, Metheetrairut C, Nugoolsuksiri S, Frayne J, Trakarnsanga K. Optimization of an erythroid culture system to reduce the cost of in vitro production of red blood cells. MethodsX. 2018;5:1626-1632 pubmed publisher
Glembotsky A, Sliwa D, Bluteau D, Balayn N, Marin Oyarzún C, Raimbault A, et al. Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia. Haematologica. 2019;104:1244-1255 pubmed publisher
Hyder A, Ehnert S, Fandrich F, Ungefroren H. Transfection of Peripheral Blood Monocytes with SOX2 Enhances Multipotency, Proliferation, and Redifferentiation into Neohepatocytes and Insulin-Producing Cells. Stem Cells Int. 2018;2018:4271875 pubmed publisher
Brookhouser N, Zhang P, Caselli R, Kim J, Brafman D. Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant-Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A). Stem Cell Res. 2018;32:145-149 pubmed publisher
Barretto K, Swanson C, Nguyen C, Annis D, Esnault S, Mosher D, et al. Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin. PLoS ONE. 2018;13:e0201320 pubmed publisher
Heshmati Y, Kharazi S, Türköz G, Chang D, Kamali Dolatabadi E, Boström J, et al. The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation. Sci Rep. 2018;8:11202 pubmed publisher
Zhang J, Xiang Z, Malaviarachchi P, Yan Y, Baltz N, Emanuel P, et al. PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia. Cell Signal. 2018;50:72-79 pubmed publisher
Camgoz A, Paszkowski Rogacz M, Satpathy S, Wermke M, Hamann M, von Bonin M, et al. STK3 is a therapeutic target for a subset of acute myeloid leukemias. Oncotarget. 2018;9:25458-25473 pubmed publisher
Berndt R, Hummitzsch L, Heß K, Albrecht M, Zitta K, Rusch R, et al. Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach. Stem Cell Res Ther. 2018;9:117 pubmed publisher
Orengo J, Radin A, Kamat V, Badithe A, Ben L, Bennett B, et al. Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement. Nat Commun. 2018;9:1421 pubmed publisher
Cesana M, Guo M, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, et al. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell. 2018;22:575-588.e7 pubmed publisher
Kotha S, Sun S, Adams A, Hayes B, Phong K, NAGAO R, et al. Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment. PLoS ONE. 2018;13:e0195082 pubmed publisher
Ferrer C, Alders M, Postma A, Park S, Klein M, Cetinbaş M, et al. An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality. Genes Dev. 2018;32:373-388 pubmed publisher
Palau A, Garz A, Diesch J, Zwick A, Malinverni R, Valero V, et al. Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes. Oncotarget. 2017;8:115002-115017 pubmed publisher
Schmitt K, Charlins P, Veselinovic M, Kinner Bibeau L, Hu S, Curlin J, et al. Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model. Virology. 2018;515:235-242 pubmed publisher
Carretta M, Brouwers Vos A, Bosman M, Horton S, Martens J, Vellenga E, et al. BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells. PLoS ONE. 2017;12:e0189102 pubmed publisher
Wilbers R, van Raaij D, Westerhof L, Bakker J, Smant G, Schots A. Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain. PLoS ONE. 2017;12:e0186317 pubmed publisher
Radecke S, Schwarz K, Radecke F. Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments. Mol Ther. 2018;26:115-131 pubmed publisher
Palpant N, Wang Y, Hadland B, Zaunbrecher R, Redd M, Jones D, et al. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis. Cell Rep. 2017;20:1597-1608 pubmed publisher
Butcher L, Ahluwalia M, Ord T, Johnston J, Morris R, Kiss Toth E, et al. Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis. Sci Rep. 2017;7:6684 pubmed publisher
Varga E, Nemes C, Bock I, Táncos Z, Berzsenyi S, Lévay G, et al. Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD). Stem Cell Res. 2017;21:19-22 pubmed publisher
Zhao H, Gulesserian S, Ganesan S, Ou J, Morrison K, Zeng Z, et al. Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC-induced Thrombocytopenia. Mol Cancer Ther. 2017;16:1877-1886 pubmed publisher
Huang J, Khan A, Au B, Barber D, Lopez Vasquez L, Prokopishyn N, et al. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease. Mol Ther Methods Clin Dev. 2017;5:241-258 pubmed publisher
Rahman N, Brauer P, Ho L, Usenko T, Tewary M, Zuniga Pflucker J, et al. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence. Nat Commun. 2017;8:15380 pubmed publisher
Zhao H, Gulesserian S, Malinao M, Ganesan S, Song J, Chang M, et al. A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise. Mol Cancer Ther. 2017;16:1866-1876 pubmed publisher
Frischmeyer Guerrerio P, Masilamani M, Gu W, Brittain E, Wood R, Kim J, et al. Mechanistic correlates of clinical responses to omalizumab in the setting of oral immunotherapy for milk allergy. J Allergy Clin Immunol. 2017;140:1043-1053.e8 pubmed publisher
Lee J, Laronde S, Collins T, Shapovalova Z, Tanasijevic B, McNicol J, et al. Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency. Cell Rep. 2017;19:20-35 pubmed publisher
Thomas D, Clare S, Sowerby J, Pardo M, Juss J, Goulding D, et al. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. J Exp Med. 2017;214:1111-1128 pubmed publisher
Trakarnsanga K, Griffiths R, Wilson M, Blair A, Satchwell T, Meinders M, et al. An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells. Nat Commun. 2017;8:14750 pubmed publisher
Schuh E, Musumeci A, Thaler F, Laurent S, Ellwart J, Hohlfeld R, et al. Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement. J Immunol. 2017;198:3081-3088 pubmed publisher
Liyanage S, Hurren R, Voisin V, Bridon G, Wang X, Xu C, et al. Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML. Blood. 2017;129:2657-2666 pubmed publisher
Schwartz J, Clayton K, Mujib S, Zhang H, Rahman A, Liu J, et al. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9. J Immunol. 2017;198:3181-3194 pubmed publisher
Chiu C, Su S, Fan W, Lai S, Tsai M, Chen S, et al. Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption. Sci Rep. 2017;7:43469 pubmed publisher
Kotini A, Chang C, Chow A, Yuan H, Ho T, Wang T, et al. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia. Cell Stem Cell. 2017;20:315-328.e7 pubmed publisher
Cárcamo Orive I, Hoffman G, Cundiff P, Beckmann N, D Souza S, Knowles J, et al. Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. Cell Stem Cell. 2017;20:518-532.e9 pubmed publisher
Pomeroy E, Lee L, Lee R, Schirm D, Temiz N, Ma J, et al. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. 2017;36:3263-3273 pubmed publisher
Huang J, Liu Y, Au B, Barber D, Arruda A, Schambach A, et al. Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML. Mol Ther Methods Clin Dev. 2016;3:16074 pubmed
Stratman A, Pezoa S, Farrelly O, Castranova D, Dye L, Butler M, et al. Interactions between mural cells and endothelial cells stabilize the developing zebrafish dorsal aorta. Development. 2017;144:115-127 pubmed publisher
Speidel A, Felk S, Reinhardt P, Sterneckert J, Gillardon F. Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells. PLoS ONE. 2016;11:e0165949 pubmed publisher
Kim H, Lee J, Heo H, Yang S, Ha K, Park W, et al. Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway. Cell Biosci. 2016;6:50 pubmed publisher
Severn C, Macedo H, Eagle M, Rooney P, Mantalaris A, Toye A. Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors. Sci Rep. 2016;6:32149 pubmed publisher
Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota S, Ota Y, et al. Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes. Immunology. 2017;150:64-73 pubmed publisher
Aflaki E, Borger D, Moaven N, Stubblefield B, Rogers S, Patnaik S, et al. A New Glucocerebrosidase Chaperone Reduces ?-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism. J Neurosci. 2016;36:7441-52 pubmed publisher
Vasu S, He S, Cheney C, Gopalakrishnan B, Mani R, Lozanski G, et al. Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts. Blood. 2016;127:2879-89 pubmed publisher
Pedroza Pacheco I, Shah D, Domogala A, Luevano M, Blundell M, Jackson N, et al. Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation. Sci Rep. 2016;6:22097 pubmed publisher
Park I, Mundy Bosse B, Whitman S, Zhang X, Warner S, Bearss D, et al. Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia. Leukemia. 2015;29:2382-9 pubmed publisher
Shima T, Iwasaki H, Yamauchi T, Kadowaki M, Kiyosuke M, Mochimaru T, et al. Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 °C. Bone Marrow Transplant. 2015;50:1195-200 pubmed publisher
Jiang X, Lim C, Li Z, Lee P, Yatim S, Guan P, et al. Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML). PLoS ONE. 2015;10:e0122983 pubmed publisher
Sterba P, Hamilton R, Saini S. Suppression of basophil Fc?RI activation by serum from active chronic idiopathic/spontaneous urticaria (CIU/CSU) subjects. J Invest Dermatol. 2015;135:1454-1456 pubmed publisher
Patterson S, Rossi J, Paweletz K, Fitzpatrick V, Begley C, Busse L, et al. Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues. PLoS ONE. 2015;10:e0122149 pubmed publisher
Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren K, et al. Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. J Immunol. 2015;194:4422-30 pubmed publisher
Dyer K, Rosenberg H. Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24). PLoS ONE. 2015;10:e0118887 pubmed publisher
Ungefroren H, Hyder A, Hinz H, Groth S, Lange H, El Sayed K, et al. Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-β. PLoS ONE. 2015;10:e0118097 pubmed publisher
Lee J, Graham M, Collins T, Lee J, Hong S, Mcnicol A, et al. Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. Stem Cells. 2015;33:1142-52 pubmed publisher
Baldwin K, Urbinati F, Romero Z, Campo Fernandez B, Kaufman M, Cooper A, et al. Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy. Stem Cells. 2015;33:1532-42 pubmed publisher
Purushothaman P, Thakker S, Verma S. Transcriptome analysis of Kaposi's sarcoma-associated herpesvirus during de novo primary infection of human B and endothelial cells. J Virol. 2015;89:3093-111 pubmed publisher
Matsuoka Y, Nakatsuka R, Sumide K, Kawamura H, Takahashi M, Fujioka T, et al. Prospectively Isolated Human Bone Marrow Cell-Derived MSCs Support Primitive Human CD34-Negative Hematopoietic Stem Cells. Stem Cells. 2015;33:1554-65 pubmed publisher
Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, et al. Targeted 25-hydroxyvitamin D3 1α-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice. Mol Ther. 2015;23:339-51 pubmed publisher
Lederle A, Su B, Holl V, Penichon J, Schmidt S, Decoville T, et al. Neutralizing antibodies inhibit HIV-1 infection of plasmacytoid dendritic cells by an FcγRIIa independent mechanism and do not diminish cytokines production. Sci Rep. 2014;4:5845 pubmed publisher
Xia C, Peng R, Chernatynskaya A, Yuan L, Carter C, Valentine J, et al. Increased IFN-?-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-? production. J Immunol. 2014;193:1024-34 pubmed publisher
Lin A, Burrascano C, Pettersson P, Ibañez C, Gruber H, Jolly D. Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity. J Virol. 2014;88:10066-77 pubmed publisher
Smith L, Ul Hasan T, Carvaines S, Van Vliet K, Yang E, WONG K, et al. Gene transfer properties and structural modeling of human stem cell-derived AAV. Mol Ther. 2014;22:1625-34 pubmed publisher
Jitkova Y, Gronda M, Hurren R, Wang X, Goard C, Jhas B, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS ONE. 2014;9:e95281 pubmed publisher
Yang C, French A, Goh P, Pagnamenta A, Mettananda S, Taylor J, et al. Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins. Br J Haematol. 2014;166:435-48 pubmed publisher
Morshed M, Hlushchuk R, Simon D, Walls A, Obata Ninomiya K, Karasuyama H, et al. NADPH oxidase-independent formation of extracellular DNA traps by basophils. J Immunol. 2014;192:5314-23 pubmed publisher
Chaurasia P, Gajzer D, Schaniel C, D Souza S, Hoffman R. Epigenetic reprogramming induces the expansion of cord blood stem cells. J Clin Invest. 2014;124:2378-95 pubmed publisher
Drewes J, Szeto G, Engle E, Liao Z, Shearer G, Zink M, et al. Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline. PLoS ONE. 2014;9:e94375 pubmed publisher
Williams M, Yousafzai Y, Cox C, Blair A, Carmody R, Sai S, et al. Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia. Blood. 2014;123:3116-27 pubmed publisher
Li X, Romain R, Park D, Scadden D, Merchant J, Arnaout M. Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89. Stem Cells. 2014;32:791-801 pubmed publisher
Jensen B, Frandsen P, Raaby E, Schiøtz P, Skov P, Poulsen L. Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells. J Leukoc Biol. 2014;95:893-901 pubmed publisher
van Wilgenburg B, Moore M, James W, Cowley S. The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. PLoS ONE. 2014;9:e86071 pubmed publisher
Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S. MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells. Stem Cells. 2014;32:1337-46 pubmed publisher
Smith A, Bowers S, Stratman A, Davis G. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS ONE. 2013;8:e85147 pubmed publisher
Klimenkova O, Ellerbeck W, Klimiankou M, Unalan M, Kandabarau S, Gigina A, et al. A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation. Blood. 2014;123:1239-49 pubmed publisher
Voskamp A, Prickett S, Mackay F, Rolland J, O Hehir R. MHC class II expression in human basophils: induction and lack of functional significance. PLoS ONE. 2013;8:e81777 pubmed publisher
Thanunchai M, Kanrai P, Wiboon ut S, Puthavathana P, Hongeng S, Thitithanyanont A. Tropism of avian influenza A (H5N1) virus to mesenchymal stem cells and CD34+ hematopoietic stem cells. PLoS ONE. 2013;8:e81805 pubmed publisher
Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, et al. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 2014;134:1246-1254 pubmed publisher
Jia X, Cong B, Zhang J, Li H, Liu W, Chang H, et al. CCK8 negatively regulates the TLR9-induced activation of human peripheral blood pDCs by targeting TRAF6 signaling. Eur J Immunol. 2014;44:489-99 pubmed publisher
Liu S, Yin L, Stroopinsky D, Rajabi H, Puissant A, Stegmaier K, et al. MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells. Blood. 2014;123:734-42 pubmed publisher
Takahashi M, Matsuoka Y, Sumide K, Nakatsuka R, Fujioka T, Kohno H, et al. CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells. Leukemia. 2014;28:1308-15 pubmed publisher
Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, et al. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell. 2013;13:459-70 pubmed publisher
Morishima T, Watanabe K, Niwa A, Hirai H, Saida S, Tanaka T, et al. Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis. Haematologica. 2014;99:19-27 pubmed publisher
Einwallner E, Jaeger E, Mitterbauer Hohendanner G, Bilban M, Simonitsch Klupp I, Steiner I, et al. Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib. Stem Cells Dev. 2013;22:3043-51 pubmed publisher
Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, et al. Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis. J Immunol. 2013;190:3959-66 pubmed publisher
Yu J, Peng Y, Wu L, Xie Z, Deng Y, Hughes T, et al. Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. PLoS ONE. 2013;8:e55934 pubmed publisher
Giannoni F, Hardee C, Wherley J, Gschweng E, Senadheera S, Kaufman M, et al. Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. Mol Ther. 2013;21:1044-54 pubmed publisher
Alysandratos K, Asadi S, Angelidou A, Zhang B, Sismanopoulos N, Yang H, et al. Neurotensin and CRH interactions augment human mast cell activation. PLoS ONE. 2012;7:e48934 pubmed publisher
Jawad M, Yu N, Seedhouse C, Tandon K, Russell N, Pallis M. Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia. BMC Cancer. 2012;12:431 pubmed publisher
Kobune M, Iyama S, Kikuchi S, Horiguchi H, Sato T, Murase K, et al. Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms. Blood Cancer J. 2012;2:e87 pubmed publisher
Li Q, Ramirez Bergeron D, Dunwoodie S, Yang Y. Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene. J Biol Chem. 2012;287:29088-100 pubmed publisher
Donhauser N, Pritschet K, Helm M, Harrer T, Schuster P, Ries M, et al. Chronic immune activation in HIV-1 infection contributes to reduced interferon alpha production via enhanced CD40:CD40 ligand interaction. PLoS ONE. 2012;7:e33925 pubmed publisher
Torrano V, Procter J, Cardus P, Greaves M, Ford A. ETV6-RUNX1 promotes survival of early B lineage progenitor cells via a dysregulated erythropoietin receptor. Blood. 2011;118:4910-8 pubmed publisher
Bond E, Liang F, Sandgren K, Smed Sorensen A, Bergman P, Brighenti S, et al. Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations. J Invest Dermatol. 2012;132:114-23 pubmed publisher
Niwa A, Heike T, Umeda K, Oshima K, Kato I, Sakai H, et al. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors. PLoS ONE. 2011;6:e22261 pubmed publisher
Uchida N, Hsieh M, Hayakawa J, Madison C, Washington K, Tisdale J. Optimal conditions for lentiviral transduction of engrafting human CD34+ cells. Gene Ther. 2011;18:1078-86 pubmed publisher
Perier A, Fregni G, Wittnebel S, Gad S, Allard M, Gervois N, et al. Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma. Oncogene. 2011;30:2622-32 pubmed publisher
Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, et al. Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome). Blood. 2011;117:839-47 pubmed publisher
Kirouac D, Ito C, Csaszar E, Roch A, Yu M, Sykes E, et al. Dynamic interaction networks in a hierarchically organized tissue. Mol Syst Biol. 2010;6:417 pubmed publisher
Gupta N, Barhanpurkar A, Tomar G, Srivastava R, Kour S, Pote S, et al. IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineage. J Immunol. 2010;185:2261-72 pubmed publisher
Ghirelli C, Zollinger R, Soumelis V. Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. Blood. 2010;115:5037-40 pubmed publisher
Stratman A, Malotte K, Mahan R, Davis M, Davis G. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood. 2009;114:5091-101 pubmed publisher
Ye L, Chang J, Lin C, Sun X, Yu J, Kan Y. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases. Proc Natl Acad Sci U S A. 2009;106:9826-30 pubmed publisher
Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, et al. Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma. Int J Cancer. 2009;125:1092-101 pubmed publisher
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, et al. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol. 2008;36:1035-46 pubmed publisher
Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, et al. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Exp Hematol. 2008;36:545-558 pubmed publisher
McCullar V, Oostendorp R, Panoskaltsis Mortari A, Yun G, Lutz C, Wagner J, et al. Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15. Exp Hematol. 2008;36:598-608 pubmed publisher
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed
Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos G, et al. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia. Exp Hematol. 2006;34:1312-22 pubmed
Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman F, Rothenberg M, et al. CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J Immunol. 2006;177:77-83 pubmed
Vassina E, Yousefi S, Simon D, Zwicky C, Conus S, Simon H. cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. Eur J Immunol. 2006;36:1975-84 pubmed
Hiroyama T, Miharada K, Aoki N, Fujioka T, Sudo K, Danjo I, et al. Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells. Exp Hematol. 2006;34:760-9 pubmed
Yokoi H, Myers A, Matsumoto K, Crocker P, Saito H, Bochner B. Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells. Allergy. 2006;61:769-76 pubmed
Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, et al. Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells. Cell Death Differ. 2006;13:1686-96 pubmed
Hanley M, Napolitano L, McCune J. Growth hormone-induced stimulation of multilineage human hematopoiesis. Stem Cells. 2005;23:1170-9 pubmed
Congote L, Difalco M, Gibbs B. Thrombospondin 1, produced by endothelial cells under the action of erythropoietin, stimulates thymidine incorporation into erythroid cells and counteracts the inhibitory action of insulin-like growth factor binding protein 3. Cytokine. 2005;30:248-53 pubmed
Féménia F, Arock M, Leriche L, Delouis C, Millet G, Ben Hamouda N, et al. Establishment and characterization of continuous hematopoietic progenitors-derived pig normal mast cell lines. Life Sci. 2005;77:808-23 pubmed
Kao C, Chen Y, Thai P, Wachi S, Huang F, Kim C, et al. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol. 2004;173:3482-91 pubmed
Bug G, Rossmanith T, Henschler R, Kunz Schughart L, Schroder B, Kampfmann M, et al. Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells. J Leukoc Biol. 2002;72:837-45 pubmed
Manz M, Miyamoto T, Akashi K, Weissman I. Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A. 2002;99:11872-7 pubmed
Aldinucci D, Poletto D, Gloghini A, Nanni P, Degan M, Perin T, et al. Expression of functional interleukin-3 receptors on Hodgkin and Reed-Sternberg cells. Am J Pathol. 2002;160:585-96 pubmed
Shih C, Hu M, Hu J, Weng Y, Yazaki P, Medeiros J, et al. A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood. 2000;95:1957-66 pubmed
Gomez Navarro J, Contreras J, Arafat W, Jiang X, Krisky D, Oligino T, et al. Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model. Gene Ther. 2000;7:43-52 pubmed
image
image 1 :
R&D Systems 203-IL-010 image 1
Recombinant Human IL-3 Protein Bioactivity
product information
brand :
R&D Systems
master code :
203-IL
SKU :
203-IL-010
product name :
Recombinant Human IL-3 Protein
description :
The Recombinant Human IL-3 Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-3 Protein has been validated for the following applications: Bioactivity.
target :
IL-3
category :
Proteins and Enzymes
sizes available :
10 ug (also 50 ug, 100 ug, 250 ug, 500 ug, 1 mg)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
15 kDa
gene symbol :
IL3
details of functionality :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.02-0.1 ng/mL. The specific activity of Recombinant Human IL-3 is approximately 1.8 x 103 IU/µg, which is calibrated against recombinant human IL-3 WHO International Standard (NIBSC code: 91/510). Specific activity is for reference purposes only and is not routinely tested.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAC08706
applications :
Bioactivity
extended description :
Earn double rewards for reviews
source :
E. coli-derived Recombinant Human IL-3 Protein
USD :
205
USD 2023 :
205 USD
product details :
Earn double rewards for reviews
alt names :
Hematopoietic growth factor, IL3, IL-3MGC79398, interleukin 3 (colony-stimulating factor, multiple), interleukin-3, Mast cell growth factor, mast-cell growth factor, MCGF, MCGFMGC79399, MULTI-CSF, multilineage-colony-stimulating factor, Multipotential colony-stimulating factor, P-cell stimulating factor, P-cell-stimulating factor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.