Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF | R&D Systems 2017-T2-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF

catalog :

2017-T2-050

quantity :

50 ug

price :

434 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Chen Y, Xu K, Piccoli L, Foglierini M, Tan J, Jin W, et al. Structural basis of malaria RIFIN binding by LILRB1-containing antibodies. Nature. 2021;592:639-643 pubmed publisher
Martinez Martin N, Ramani S, Hackney J, Tom I, Wranik B, Chan M, et al. The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation. Nat Commun. 2016;7:11473 pubmed publisher
Li N, Fu L, Uchtenhagen H, Achour A, Burshtyn D. Cis association of leukocyte Ig-like receptor 1 with MHC class I modulates accessibility to antibodies and HCMV UL18. Eur J Immunol. 2013;43:1042-52 pubmed publisher
Baudhuin J, Lesport E, Sousa S, Migraine J, Vigneron J, Lemaoult J, et al. HLA-G inhibition of NK-cell cytolytic function is uncoupled from tumor cell lipid raft reorganization. Eur J Immunol. 2012;42:700-9 pubmed publisher
Verloes A, Van De Velde H, Lemaoult J, Mateizel I, Cauffman G, Horn P, et al. HLA-G expression in human embryonic stem cells and preimplantation embryos. J Immunol. 2011;186:2663-71 pubmed publisher

image

image 1 :

Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein Binding Activity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2017-T2

SKU :

2017-T2-050

product name :

Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF

Description :

The Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

LILRB1/CD85j/ILT2

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

106 kDa, reducing conditions

theoretical molecular weight :

73.8 kDa (monomer)

gene symbol :

LILRB1

details of functionality :

Measured by its ability to support the adhesion of HSB2 human peripheral blood acute lymphoblastic leukemia cells. Immobilized Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera at 5 µg/mL, 100 µL/well can support 60-80% HSB2 cell adhesion, when 1 x 105 cells were added in each well of a 96-well plate.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q8NHL6

applications :

Bioactivity

source :

NS0-derived Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein

USD :

434 USD

alt names :

CD85 antigen-like family member J, CD85J, CD85j antigen, Ig-like transcript 2, ILT2, ILT-2, ILT2FLJ37515, Immunoglobulin-like transcript 2, leukocyte Ig-like receptor-1, Leukocyte immunoglobulin-like receptor 1, leukocyte immunoglobulin-like receptor subfamily B member 1, leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR1, LIR1LIR-1MIR-7CD85MIR7CD85 antigen, member 1, MIR7, Monocyte/macrophage immunoglobulin-like receptor 7

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage