Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF | R&D Systems 2017-T2-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF

catalog :

2017-T2-050

quantity :

50 ug

price :

443 USD

citations: 5

Reference
Chen Y, Xu K, Piccoli L, Foglierini M, Tan J, Jin W, et al. Structural basis of malaria RIFIN binding by LILRB1-containing antibodies. Nature. 2021;592:639-643 pubmed publisher
Martinez Martin N, Ramani S, Hackney J, Tom I, Wranik B, Chan M, et al. The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation. Nat Commun. 2016;7:11473 pubmed publisher
Li N, Fu L, Uchtenhagen H, Achour A, Burshtyn D. Cis association of leukocyte Ig-like receptor 1 with MHC class I modulates accessibility to antibodies and HCMV UL18. Eur J Immunol. 2013;43:1042-52 pubmed publisher
Baudhuin J, Lesport E, Sousa S, Migraine J, Vigneron J, Lemaoult J, et al. HLA-G inhibition of NK-cell cytolytic function is uncoupled from tumor cell lipid raft reorganization. Eur J Immunol. 2012;42:700-9 pubmed publisher
Verloes A, Van De Velde H, Lemaoult J, Mateizel I, Cauffman G, Horn P, et al. HLA-G expression in human embryonic stem cells and preimplantation embryos. J Immunol. 2011;186:2663-71 pubmed publisher

product information

master code :

2017-T2

SKU :

2017-T2-050

product name :

Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

LILRB1/CD85j/ILT2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

106 kDa, reducing conditions

theoretical molecular weight :

73.8 kDa (monomer)

gene symbol :

LILRB1

details of functionality :

Measured by its ability to support the adhesion of HSB2 human peripheral blood acute lymphoblastic leukemia cells. Immobilized Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera at 5 ╡g/mL, 100 ╡L/well can support 60-80% HSB2 cell adhesion, when 1 x 105 cells were added in each well of a 96-well plate.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human LILRB1/CD85j/ILT2 Fc Chimera Protein Binding Activity

accessionNumbers :

Q8NHL6

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human LILRB1/CD85j/ILT2 protein Human LILRB1/CD85j/ILT2 (Gly24-His458) Accession # Q8NHL6 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

443 USD

alt names :

CD85 antigen-like family member J, CD85J, CD85j antigen, Ig-like transcript 2, ILT2, ILT-2, ILT2FLJ37515, Immunoglobulin-like transcript 2, leukocyte Ig-like receptor-1, Leukocyte immunoglobulin-like receptor 1, leukocyte immunoglobulin-like receptor subfamily B member 1, leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR1, LIR1LIR-1MIR-7CD85MIR7CD85 antigen, member 1, MIR7, Monocyte/macrophage immunoglobulin-like receptor 7

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.