Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein, CF | R&D Systems 2014-KR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein, CF

catalog :

2014-KR-050

quantity :

50 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Fittje P, H x153 lzemer A, Garcia Beltran W, Vollmers S, Niehrs A, Hagemann K, et al. HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells. PLoS Pathog. 2022;18:e1010572 pubmed publisher
Thiruchelvam Kyle L, Hoelsbrekken S, Saether P, Bjørnsen E, Pende D, Fossum S, et al. The Activating Human NK Cell Receptor KIR2DS2 Recognizes a ?2-Microglobulin-Independent Ligand on Cancer Cells. J Immunol. 2017;198:2556-2567 pubmed publisher
Cifaldi L, Romania P, Falco M, Lorenzi S, Meazza R, Petrini S, et al. ERAP1 regulates natural killer cell function by controlling the engagement of inhibitory receptors. Cancer Res. 2015;75:824-34 pubmed publisher
Cassidy S, Mukherjee S, Myint T, Mbiribindi B, North H, Traherne J, et al. Peptide selectivity discriminates NK cells from KIR2DL2- and KIR2DL3-positive individuals. Eur J Immunol. 2015;45:492-500 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2014-KR

SKU :

2014-KR-050

product name :

Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein, CF

Description :

The Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

KIR2DL3/CD158b2

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

66-75 kDa, reducing conditions

theoretical molecular weight :

51.2 kDa (monomer)

gene symbol :

KIR2DL3

details of functionality :

Measured by its ability to bind HEK293T human embryonic kidney cells in a flow cytometry assay. When 10 µg of Recombinant Human KIR2DL3/CD158b2 Fc Chimera is added to 5 x 105 HEK293T cells, 20% of the cells will bind to the protein.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P43628

applications :

Bioactivity

source :

NS0-derived Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein

USD :

447 USD

alt names :

CD158 antigen-like family member B2, CD158b2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, nkat2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage