Recombinant Mouse NOV/CCN3 Protein, CF | R&D Systems 1976-NV-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse NOV/CCN3 Protein, CF

catalog :

1976-NV-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Luan Y, Zhang H, Ma K, Liu Y, Lu H, Chen X, et al. CCN3/NOV Regulates Proliferation and Neuronal Differentiation in Mouse Hippocampal Neural Stem Cells via the Activation of the Notch/PTEN/AKT Pathway. Int J Mol Sci. 2023;24: pubmed publisher
Murata K, Jadhav U, Madha S, van Es J, Dean J, Cavazza A, et al. Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells. Cell Stem Cell. 2020;26:377-390.e6 pubmed publisher
Dombrowski Y, O Hagan T, Dittmer M, Penalva R, Mayoral S, Bankhead P, et al. Regulatory T cells promote myelin regeneration in the central nervous system. Nat Neurosci. 2017;20:674-680 pubmed publisher
Valenti G, Quinn H, Heynen G, Lan L, Holland J, Vogel R, et al. Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors. Cancer Res. 2017;77:2134-2147 pubmed publisher
Riser B, Najmabadi F, Perbal B, Peterson D, Rambow J, Riser M, et al. CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease. Am J Pathol. 2009;174:1725-34 pubmed publisher

product information

brand :

R&D Systems

master code :

1976-NV

SKU :

1976-NV-050

product name :

Recombinant Mouse NOV/CCN3 Protein, CF

unit size :

50 ug

seo description :

The Recombinant Mouse NOV/CCN3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse NOV/CCN3 Protein, CF has been validated for the following applications: Bioactivity.

target :

NOV/CCN3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

54 kDa, reducing conditions

theoretical molecular weight :

37.4 kDa

gene symbol :

Nov

details of functionality :

Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion. Ball, D.K. etáal . (2003) Reproduction 125 :271. rmNOV, immobilized at 10 ╡g/mL, 100 ╡L/well, will mediate 25% Balbc/3T3 cell adhesion (3 x 104 cells/well added).

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q64299

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse NOV/CCN3 Protein, CF

USD :

432 USD

alt names :

CCN family member 3, CCN3, CCN3IGF-binding protein 9, IBP-9, IGFBP-9, IGFBP9novH, Insulin-like growth factor-binding protein 9, nephroblastoma overexpressed gene, Nephroblastoma-overexpressed gene protein homolog, NOVH, protein NOV homolog

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 2 weeks, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage