Recombinant Human IL-24 Protein | R&D Systems 1965-IL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-24 Protein

catalog :

1965-IL

quantity :

25 ug

price :

339 USD

citations: 15

Reference
Delic D, Wolk K, Schmid R, Gabrielyan O, Christou D, Rieber K, et al. Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients. J Dermatol Sci. 2020;97:9-20 pubmed publisher
Kumar N, Moideen K, Banurekha V, Nair D, Babu S. Modulation of Th1/Tc1 and Th17/Tc17 responses in pulmonary tuberculosis by IL-20 subfamily of cytokines. Cytokine. 2018;108:190-196 pubmed publisher
Kawada S, Nagasawa Y, Kawabe M, Ohyama H, Kida A, Kato Kogoe N, et al. Iron-induced calcification in human aortic vascular smooth muscle cells through interleukin-24 (IL-24), with/without TNF-alpha. Sci Rep. 2018;8:658 pubmed publisher
Ross B, Gao N, Cui X, Standiford T, Xu J, Yu F. IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas. J Immunol. 2017;198:3536-3547 pubmed publisher
Pap D, Sziksz E, Kiss Z, Rokonay R, Veres Székely A, Lippai R, et al. Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inflammatio. Kidney Blood Press Res. 2017;42:16-32 pubmed publisher
Tsaousi A, Witte E, Witte K, Röwert Huber H, Volk H, Sterry W, et al. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations. Mediators Inflamm. 2016;2016:4097574 pubmed
Kumari S, Bonnet M, Ulvmar M, Wolk K, Karagianni N, Witte E, et al. Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice. Immunity. 2013;39:899-911 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Heinemann A, He Y, Zimina E, Boerries M, Busch H, Chmel N, et al. Induction of phenotype modifying cytokines by FERMT1 mutations. Hum Mutat. 2011;32:397-406 pubmed publisher
Maarof G, Bouchet Delbos L, Gary Gouy H, Durand Gasselin I, Krzysiek R, Dalloul A. Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells. Blood. 2010;115:1718-26 pubmed publisher
Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, et al. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur J Immunol. 2009;39:2779-88 pubmed publisher
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, et al. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int J Cancer. 2009;125:367-73 pubmed publisher
Wu B, Huang C, Kato Maeda M, Hopewell P, Daley C, Krensky A, et al. IL-24 modulates IFN-gamma expression in patients with tuberculosis. Immunol Lett. 2008;117:57-62 pubmed publisher
Tahara I, Miyake K, Hanawa H, Kurai T, Hirai Y, Ishizaki M, et al. Systemic cancer gene therapy using adeno-associated virus type 1 vector expressing MDA-7/IL24. Mol Ther. 2007;15:1805-11 pubmed
Sa S, Valdez P, Wu J, Jung K, Zhong F, Hall L, et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol. 2007;178:2229-40 pubmed

product information

brand :

R&D Systems

master code :

1965-IL

SKU :

1965-IL-025

product name :

Recombinant Human IL-24 Protein

description :

The Recombinant Human IL-24 Protein from R&D Systems is derived from NS0. The Recombinant Human IL-24 Protein has been validated for the following applications: Bioactivity.

target :

IL-24

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

26-35 kDa, reducing conditions

theoretical molecular weight :

19.5 kDa

gene symbol :

IL24

details of functionality :

Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R beta . The ED50 for this effect is 15-150 pg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

1965-IL

accessionNumbers :

Q13007

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human IL-24 protein Met28-Leu206, with a C-terminal 10-His tag

2020 USD :

339

2021 USD :

339 USD

alt names :

C49A, FISP, IL10B, IL24, IL-24, interleukin 24, mda-7, MDA7MOB5, melanocyte-associated Mda-7, melanoma differentiation association protein 7, Melanoma differentiation-associated gene 7 protein, MOB-5, ST16, ST16interleukin-24, suppression of tumorigenicity 16 (melanoma differentiation), Suppression of tumorigenicity 16 protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.