Recombinant Mouse Fc gamma RIII/CD16 Protein, CF | R&D Systems 1960-FC-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Fc gamma RIII/CD16 Protein, CF

catalog :

1960-FC-050

quantity :

50 ug

price :

443 USD

citations: 6

Reference
Pascual Pasto G, McIntyre B, Hines M, Giudice A, Garcia Gerique L, Hoffmann J, et al. CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma. Nat Commun. 2024;15:7141 pubmed publisher
Dodagatta Marri E, Ma H, Liang B, Li J, Meyer D, Chen S, et al. Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy. Cell Rep. 2021;36:109309 pubmed publisher
Au K, Park S, Wang A. Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy. Sci Adv. 2020;6:eaba8564 pubmed publisher
Beppler J, Mkaddem S, Michaloski J, Honorato R, Velasco I, de Oliveira P, et al. Negative regulation of bacterial killing and inflammation by two novel CD16 ligands. Eur J Immunol. 2016;46:1926-35 pubmed publisher
Shanmugarajan S, Beeson C, Reddy S. Osteoclast inhibitory peptide-1 binding to the Fc gammaRIIB inhibits osteoclast differentiation. Endocrinology. 2010;151:4389-99 pubmed publisher
Hirano M, Davis R, Fine W, Nakamura S, Shimizu K, Yagi H, et al. IgEb immune complexes activate macrophages through FcgammaRIV binding. Nat Immunol. 2007;8:762-71 pubmed publisher

product information

master code :

1960-FC

SKU :

1960-FC-050

product name :

Recombinant Mouse Fc gamma RIII/CD16 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Fc gamma RIII/CD16 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Fc gamma RIII/CD16 Protein, CF has been validated for the following applications: Binding Activity.

target :

Fc gamma RIII (CD16)

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

30-45 kDa, reducing conditions

theoretical molecular weight :

22.5 kDa

gene symbol :

Fcgr3

details of functionality :

Measured by its ability to bind mouse IgG with an estimated Kd 15 nM.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P08508.1

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse Fc gamma RIII (CD16) protein Ala31-Thr215, with a C-terminal 10-His tag

source short :

NS0

USD :

443 USD

alt names :

CD16, CD16A, Fc fragment of IgG receptor IIIa, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 3 months, -20 to -70 ░C under sterile conditions after opening.