Recombinant Human B7-H3 His-tag Protein | R&D Systems 1949-B3-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human B7-H3 His-tag Protein

catalog :

1949-B3-050

quantity :

50 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Burvenich I, Parakh S, Lee F, Guo N, Liu Z, Gan H, et al. Molecular imaging of T cell co-regulator factor B7-H3 with 89Zr-DS-5573a. Theranostics. 2018;8:4199-4209 pubmed publisher
Quandt D, Fiedler E, Muller A, Marsch W, Seliger B. High constitutive B7-H3 expression on human keratinocytes supports T cell immunity. J Dermatol Sci. 2017;87:82-85 pubmed publisher
Ingebrigtsen V, Boye K, Nesland J, Nesbakken A, Flatmark K, Fodstad Ø. B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome. BMC Cancer. 2014;14:602 pubmed publisher
Zhang G, Wang J, Kelly J, Gu G, Hou J, Zhou Y, et al. B7-H3 augments the inflammatory response and is associated with human sepsis. J Immunol. 2010;185:3677-84 pubmed publisher

product information

brand :

R&D Systems

master code :

1949-B3

SKU :

1949-B3-050

product name :

Recombinant Human B7-H3 His-tag Protein

unit size :

50 ug

seo description :

The Recombinant Human B7-H3 His-tag Protein from R&D Systems is derived from NS0. The Recombinant Human B7-H3 His-tag Protein has been validated for the following applications: Bioactivity.

target :

B7-H3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

38-48 kDa, reducing conditions

theoretical molecular weight :

24.8 kDa

gene symbol :

CD276

details of functionality :

Measured in a cell proliferation assay using mouse CD4+ cells in the presence of anti-CD3. The ED50 for this effect is 3-12 ╡g/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_079516

applications :

Bioactivity

source :

NS0-derived Recombinant Human B7-H3 His-tag Protein

USD :

443 USD

alt names :

B7H3, B7H34Ig-B7-H3, B7-H3B7 homolog 3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage