Recombinant Human Pentraxin 2/SAP His-tag Protein, CF | R&D Systems 1948-SAB-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Pentraxin 2/SAP His-tag Protein, CF

catalog :

1948-SAB-050

quantity :

50 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Wang L, Liang D, Huang Y, Chen Y, Yang X, Huang Z, et al. SAP deficiency aggravates periodontitis possibly via C5a-C5aR signaling-mediated defective macrophage phagocytosis of Porphyromonas gingivalis. J Adv Res. 2022;: pubmed publisher
Nakagawa N, Barron L, Gomez I, Johnson B, Roach A, Kameoka S, et al. Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease. JCI Insight. 2016;1:e87446 pubmed publisher
Roy N, Ohtani K, Hidaka Y, Amano Y, Matsuda Y, Mori K, et al. Three pentraxins C-reactive protein, serum amyloid p component and pentraxin 3 mediate complement activation using Collectin CL-P1. Biochim Biophys Acta Gen Subj. 2017;1861:1-14 pubmed publisher
Haudek S, Trial J, Xia Y, Gupta D, Pilling D, Entman M. Fc receptor engagement mediates differentiation of cardiac fibroblast precursor cells. Proc Natl Acad Sci U S A. 2008;105:10179-84 pubmed publisher

product information

brand :

R&D Systems

master code :

1948-SAB

SKU :

1948-SAB-050

product name :

Recombinant Human Pentraxin 2/SAP His-tag Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human Pentraxin 2/SAP His-tag Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Pentraxin 2/SAP His-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

Pentraxin 2/SAP

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MOPS, NaCl and CaCl2 with Trehalose.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

27-33 kDa, reducing conditions

theoretical molecular weight :

25 kDa

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Fc gamma RllA/CD32a (R167) (Catalog # 1330-CD ) is immobilized at 2 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human Pentraxin 2/SAP that produces 50% of the optimal binding response is 0.175-1 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human Pentraxin 2/SAP His-tag Protein Binding Activity

accessionNumbers :

P02743

applications :

Bioactivity

source :

NS0-derived Recombinant Human Pentraxin 2/SAP His-tag Protein, CF

USD :

443 USD

alt names :

9.5S alpha-1-glycoprotein, amyloid P component, serum, APCS, MGC88159, PTX2, PTX2serum amyloid P-component, SAP, SAPpentaxin-related, Serum Amyloid P component

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage