Recombinant Human TC-PTP (aa 2-314) Protein, CF | R&D Systems 1930-PT-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TC-PTP (aa 2-314) Protein, CF

catalog :

1930-PT-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Duval R, Bui L, Mathieu C, Nian Q, Berthelet J, Xu X, et al. Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling. J Biol Chem. 2019;294:12483-12494 pubmed publisher
Ingebrigtsen R, Hansen E, Andersen J, Eilertsen H. Field sampling marine plankton for biodiscovery. Sci Rep. 2017;7:15863 pubmed publisher
Borza C, Chen X, Mathew S, Mont S, Sanders C, Zent R, et al. Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. J Biol Chem. 2010;285:40114-24 pubmed publisher

product information

master code :

1930-PT

SKU :

1930-PT-050

product name :

Recombinant Human TC-PTP (aa 2-314) Protein, CF

unit size :

50 ug

description :

The Recombinant Human TC-PTP (aa 2-314) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human TC-PTP (aa 2-314) Protein, CF has been validated for the following applications: Enzyme Activity.

target :

TC-PTP

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in HEPES, NaCl, Glycerol and Betamercaptoethanol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

38 kDa, reducing conditions

theoretical molecular weight :

37 kDa

gene symbol :

PTPN2

details of functionality :

Measured by its ability to dephosphorylate a tyrosine residue in a peptide containing the EGFR Y992 phosphorylation site (Catalog # ES006 ). The specific activity is 30 ╡mol/min/mg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q96AU5

applications :

Enzyme Activity

source long :

E. coli -derived human TC-PTP protein Thr2-Asn314, with an N-terminal Met and 6-His tag

source short :

E. coli

USD :

432 USD

alt names :

protein tyrosine phosphatase, non-receptor type 2, PTP2, PTPN2, PTPTPTN2, T-cell protein tyrosine phosphatase, T-cell protein-tyrosine phosphatase, TCELLPTP, TCPTP, TC-PTP, TCPTPEC 3.1.3.48, tyrosine-protein phosphatase non-receptor type 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage