Recombinant Human SP-D Protein, CF | R&D Systems 1920-SP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human SP-D Protein, CF

catalog :

1920-SP

quantity :

50 ug

price :

339 USD

citations: 5

Reference
Wong S, Rani M, Dodagatta Marri E, Ibrahim Granet O, Kishore U, Bayry J, et al. Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to Aspergillus fumigatus spores. J Biol Chem. 2018;293:4901-4912 pubmed publisher
Soltysiak K, van Schaik E, Samuel J. Surfactant Protein D Binds to Coxiella burnetii and Results in a Decrease in Interactions with Murine Alveolar Macrophages. PLoS ONE. 2015;10:e0136699 pubmed publisher
Bratcher P, Gaggar A. Factors influencing the measurement of plasma/serum surfactant protein D levels by ELISA. PLoS ONE. 2014;9:e111466 pubmed publisher
Bratcher P, Weathington N, Nick H, Jackson P, Snelgrove R, Gaggar A. MMP-9 cleaves SP-D and abrogates its innate immune functions in vitro. PLoS ONE. 2012;7:e41881 pubmed publisher
Ruge C, Schaefer U, Herrmann J, Kirch J, Cañadas O, Echaide M, et al. The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles. PLoS ONE. 2012;7:e40775 pubmed publisher

product information

brand :

R&D Systems

master code :

1920-SP

SKU :

1920-SP-050

product name :

Recombinant Human SP-D Protein, CF

description :

The Recombinant Human SP-D Protein, CF from R&D Systems is derived from NS0. The Recombinant Human SP-D Protein, CF has been validated for the following applications: Binding Activity.

target :

SP-D

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

40-48 kDa, reducing conditions

theoretical molecular weight :

35.4 kDa (monomer)

gene symbol :

SFTPD

details of functionality :

Measured by its ability to bind fluorescein-conjugated E. coli Bioparticles. Kuan, S.F. et al . (1992) J. Clin. Invest. 90 :97. The ED50 for this effect is 0.5-3 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

1920-SP

accessionNumbers :

P35247

applications :

Binding Activity

source :

Mouse myeloma cell line, NS0-derived human SP-D protein Ala21-Phe375 (Glu22Gly)

2020 USD :

339

2021 USD :

339 USD

alt names :

COLEC7collectin-7, collectin 7, Collectin-7, Lung surfactant protein D, PSPD, PSP-D, SFTP4, SFTP4pulmonary surfactant-associated protein D, SFTPD, SPD, SP-Dpulmonary surfactant apoprotein, surfactant protein D, surfactant, pulmonary-associated protein D, surfactant-associated protein, pulmonary 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.