Recombinant Human SP-D Protein, CF | R&D Systems 1920-SP-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human SP-D Protein, CF

catalog :

1920-SP-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Delli xe8 re S, Chauvin C, Wong S, Gressler M, Possetti V, Parente R, et al. Interplay between host humoral pattern recognition molecules controls undue immune responses against Aspergillus fumigatus. Nat Commun. 2024;15:6966 pubmed publisher
Hata K, Tsubouchi K, Suzuki K, Eto D, Ando H, Yanagihara T, et al. Surfactant protein D prevents mucin overproduction in airway goblet cells via SIRPα. Sci Rep. 2024;14:1799 pubmed publisher
Zoued A, Zhang H, Zhang T, Giorgio R, Kuehl C, Fakoya B, et al. Proteomic analysis of the host-pathogen interface in experimental cholera. Nat Chem Biol. 2021;17:1199-1208 pubmed publisher
Tajima Y, Tsuruta M, Hasegawa H, Okabayashi K, Ishida T, Yahagi M, et al. Association of surfactant protein D with pulmonary metastases from colon cancer. Oncol Lett. 2020;20:322 pubmed publisher
Wong S, Rani M, Dodagatta Marri E, Ibrahim Granet O, Kishore U, Bayry J, et al. Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to Aspergillus fumigatus spores. J Biol Chem. 2018;293:4901-4912 pubmed publisher
Soltysiak K, van Schaik E, Samuel J. Surfactant Protein D Binds to Coxiella burnetii and Results in a Decrease in Interactions with Murine Alveolar Macrophages. PLoS ONE. 2015;10:e0136699 pubmed publisher
Bratcher P, Weathington N, Nick H, Jackson P, Snelgrove R, Gaggar A. MMP-9 cleaves SP-D and abrogates its innate immune functions in vitro. PLoS ONE. 2012;7:e41881 pubmed publisher
Ruge C, Schaefer U, Herrmann J, Kirch J, Cañadas O, Echaide M, et al. The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles. PLoS ONE. 2012;7:e40775 pubmed publisher

product information

brand :

R&D Systems

master code :

1920-SP

SKU :

1920-SP-050

product name :

Recombinant Human SP-D Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human SP-D Protein, CF from R&D Systems is derived from NS0. The Recombinant Human SP-D Protein, CF has been validated for the following applications: Binding Activity.

target :

SP-D

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

40-48 kDa, reducing conditions

theoretical molecular weight :

35.4 kDa (monomer)

gene symbol :

SFTPD

details of functionality :

Measured by its ability to bind fluorescein-conjugated E. coli Bioparticles. Kuan, S.F. et al . (1992) J. Clin. Invest. 90 :97. The ED50 for this effect is 0.5-3 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P35247

applications :

Binding Activity

source :

NS0-derived Recombinant Human SP-D Protein, CF

USD :

432 USD

alt names :

COLEC7collectin-7, collectin 7, Collectin-7, Lung surfactant protein D, PSPD, PSP-D, SFTP4, SFTP4pulmonary surfactant-associated protein D, SFTPD, SPD, SP-Dpulmonary surfactant apoprotein, surfactant protein D, surfactant, pulmonary-associated protein D, surfactant-associated protein, pulmonary 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage