Recombinant Human sFRP-3 Protein, CF | R&D Systems 192-SF-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human sFRP-3 Protein, CF

catalog :

192-SF-010/CF

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Schivo S, Khurana S, Govindaraj K, Scholma J, Kerkhofs J, Zhong L, et al. ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease. Cell Signal. 2020;68:109471 pubmed publisher
Pachori A, Madan M, Nunez Lopez Y, Yi F, Meyer C, Seyhan A. Reduced skeletal muscle secreted frizzled-related protein 3 is associated with inflammation and insulin resistance. Obesity (Silver Spring). 2017;25:697-703 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Ekström E, Sherwood V, Andersson T. Methylation and loss of Secreted Frizzled-Related Protein 3 enhances melanoma cell migration and invasion. PLoS ONE. 2011;6:e18674 pubmed publisher
Giuliani N, Morandi F, Tagliaferri S, Lazzaretti M, Donofrio G, Bonomini S, et al. Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. Cancer Res. 2007;67:7665-74 pubmed
Lane N, Lian K, Nevitt M, Zmuda J, Lui L, Li J, et al. Frizzled-related protein variants are risk factors for hip osteoarthritis. Arthritis Rheum. 2006;54:1246-54 pubmed

product information

brand :

R&D Systems

master code :

192-SF/CF

SKU :

192-SF-010/CF

product name :

Recombinant Human sFRP-3 Protein, CF

unit size :

10 ug

seo description :

The Recombinant Human sFRP-3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human sFRP-3 Protein, CF has been validated for the following applications: Bioactivity.

target :

sFRP-3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

38 kDa, reducing conditions

theoretical molecular weight :

35 kDa

gene symbol :

FRZB

details of functionality :

Measured by its ability to inhibit proliferation in MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 1-4á╡g/mL. Optimal concentrations should be determined by each laboratory for each application.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAB51298

applications :

Bioactivity

source :

NS0-derived Recombinant Human sFRP-3 Protein, CF

extended description :

An improved and economically priced alternative is available.

USD :

432 USD

product details :

An improved and economically priced alternative is available.

alt names :

FIZ, FREOS1, Frezzled, Fritz, frizzled-related protein, Frizzled-related protein 1, FRP, FRP-3, FRZB, Frzb1, FrzB-1, FRZB1sFRP-3, FRZB-PEN, FZRB, hFIZ, secreted frizzled-related protein 3, sFRP3, SFRP3frezzled, SRFP3frizzled homolog-related

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage