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company name :
R&D Systems
product type :
protein
product name :
Human Fibronectin Protein, CF
catalog :
1918-FN-02M
quantity :
2 mg
price :
322 USD
more info or order :
citations: 39
Reference
Makhlouf A, Wang A, Sato N, Rosa V, Shahbazi M. Integrin signaling in pluripotent cells acts as a gatekeeper of mouse germline entry. Sci Adv. 2024;10:eadk2252 pubmed publisher
Munuera I, Aragón Navas A, Villacampa P, Gonzalez Cela M, Sub xed as M, Pablo L, et al. Chronic Glaucoma Induced in Rats by a Single Injection of Fibronectin-Loaded PLGA Microspheres: IOP-Dependent and IOP-Independent Neurodegeneration. Int J Mol Sci. 2023;25: pubmed publisher
Matkovic Leko I, Schneider R, Thimraj T, Schrode N, Beitler D, Liu H, et al. A distal lung organoid model to study interstitial lung disease, viral infection and human lung development. Nat Protoc. 2023;18:2283-2312 pubmed publisher
Parween F, Singh S, Zhang H, Kathuria N, Otaizo Carrasquero F, Shamsaddini A, et al. Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells. bioRxiv. 2023;: pubmed publisher
Gioelli N, Neilson L, Wei N, Villari G, Chen W, Kuhle B, et al. Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability. Nat Commun. 2022;13:4188 pubmed publisher
Ren J, Li C, Zhang M, Wang H, Xie Y, Tang Y. A Step-by-Step Refined Strategy for Highly Efficient Generation of Neural Progenitors and Motor Neurons from Human Pluripotent Stem Cells. Cells. 2021;10: pubmed publisher
Heydt Q, Xintaropoulou C, Clear A, Austin M, Pislariu I, Miraki Moud F, et al. Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence. Nat Commun. 2021;12:5507 pubmed publisher
Astarita C, Palchetti S, Massaro Giordano M, Di Domenico M, Petrillo F, Boffo S, et al. Artificial Protein Coronas Enable Controlled Interaction with Corneal Epithelial Cells: New Opportunities for Ocular Drug Delivery. Pharmaceutics. 2021;13: pubmed publisher
Bai X, Yang W, Luan X, Li H, Li H, Tian D, et al. Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection. Cell Rep. 2021;35:109159 pubmed publisher
Rodrigues Toste de Carvalho A, Liu H, Chen Y, Porotto M, Moscona A, Snoeck H. The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D. Nat Protoc. 2021;16:1802-1829 pubmed publisher
Bhat S, Viswanathan P, Chandanala S, Prasanna S, Seetharam R. Expansion and characterization of bone marrow derived human mesenchymal stromal cells in serum-free conditions. Sci Rep. 2021;11:3403 pubmed publisher
Hellinger J, Schömel F, Buse J, Lenz C, Bauerschmitz G, Emons G, et al. Identification of drivers of breast cancer invasion by secretome analysis: insight into CTGF signaling. Sci Rep. 2020;10:17889 pubmed publisher
Rai R, Romito M, Rivers E, Turchiano G, Blattner G, Vetharoy W, et al. Targeted gene correction of human hematopoietic stem cells for the treatment of Wiskott - Aldrich Syndrome. Nat Commun. 2020;11:4034 pubmed publisher
Ahn S, Maeng Y, Kim Y, Choe Y, Hwang H, Hyun Y. In vivo monitoring of dynamic interaction between neutrophil and human umbilical cord blood-derived mesenchymal stem cell in mouse liver during sepsis. Stem Cell Res Ther. 2020;11:44 pubmed publisher
Zhai L, Liu Y, Zhao W, Chen Q, Guo T, Wei W, et al. Aerobic and resistance training enhances endothelial progenitor cell function via upregulation of caveolin-1 in mice with type 2 diabetes. Stem Cell Res Ther. 2020;11:10 pubmed publisher
Ayala Nuñez N, Follain G, Delalande F, Hirschler A, Partiot E, Hale G, et al. Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells. Nat Commun. 2019;10:4430 pubmed publisher
Nath Sarma S, Nagano R, Ohsako S. Tyroxine Hydroxylase-Positive Neuronal Cell Population is Increased by Temporal Dioxin Exposure at Early Stage of Differentiation from Human Embryonic Stem Cells. Int J Mol Sci. 2019;20: pubmed publisher
Karpova D, Rettig M, Ritchey J, Cancilla D, Christ S, Gehrs L, et al. Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells. J Clin Invest. 2019;129:2745-2759 pubmed publisher
Yang Z, Chen H, Shu M, Zhang Y, Xue L, Lin Y. DLC2 operates as a tumor suppressor gene in breast cancer via the RhoGTPase pathway. Oncol Lett. 2019;17:2107-2116 pubmed publisher
Elamaa H, Kihlström M, Kapiainen E, Kaakinen M, Miinalainen I, Ragauskas S, et al. Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina. elife. 2018;7: pubmed publisher
He T, Sun R, Li Y, Katusic Z. Effects of Brain-Derived Neurotrophic Factor on MicroRNA Expression Profile in Human Endothelial Progenitor Cells. Cell Transplant. 2018;27:1005-1009 pubmed publisher
Wang J, Liu J, Zhou R, Ding X, Zhang Q, Zhang C, et al. Zika virus infected primary microglia impairs NPCs proliferation and differentiation. Biochem Biophys Res Commun. 2018;497:619-625 pubmed publisher
Hong M, Cheng H, Song L, Wang W, Wang Q, Xu D, et al. Wogonin Suppresses the Activity of Matrix Metalloproteinase-9 and Inhibits Migration and Invasion in Human Hepatocellular Carcinoma. Molecules. 2018;23: pubmed publisher
Sarvi S, Patel H, Li J, Dodd G, Creedon H, Muir M, et al. Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis. Cancer Res. 2018;78:1484-1496 pubmed publisher
Langer E, Kendsersky N, Daniel C, Kuziel G, Pelz C, Murphy K, et al. ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells. Oncogene. 2018;37:1005-1019 pubmed publisher
Kumar A, Delgado A, Piazuelo M, Van Kaer L, Olivares Villagómez D. Innate CD8αα+ lymphocytes enhance anti-CD40 antibody-mediated colitis in mice. Immun Inflamm Dis. 2017;5:109-123 pubmed publisher
Gu Y, Liu S, Zhang X, Chen G, Liang H, Yu M, et al. Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer. Protein Cell. 2017;8:455-466 pubmed publisher
Mikuła Pietrasik J, Uruski P, Sosińska P, Maksin K, Piotrowska Kempisty H, Kucińska M, et al. Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases. Cell Death Dis. 2016;7:e2565 pubmed publisher
Mana G, Clapero F, Panieri E, Panero V, Böttcher R, Tseng H, et al. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat Commun. 2016;7:13546 pubmed publisher
Cattavarayane S, Palovuori R, Tanjore Ramanathan J, Manninen A. α6β1- and αV-integrins are required for long-term self-renewal of murine embryonic stem cells in the absence of LIF. BMC Cell Biol. 2015;16:3 pubmed publisher
Huang Y, Clarke F, Karimi M, Roy N, Williamson E, Okumura M, et al. CRK proteins selectively regulate T cell migration into inflamed tissues. J Clin Invest. 2015;125:1019-32 pubmed publisher
Liang H, Liu M, Yan X, Zhou Y, Wang W, Wang X, et al. miR-193a-3p functions as a tumor suppressor in lung cancer by down-regulating ERBB4. J Biol Chem. 2015;290:926-40 pubmed publisher
Wang N, Liang H, Zhou Y, Wang C, Zhang S, Pan Y, et al. miR-203 suppresses the proliferation and migration and promotes the apoptosis of lung cancer cells by targeting SRC. PLoS ONE. 2014;9:e105570 pubmed publisher
Ranga A, Gobaa S, Okawa Y, Mosiewicz K, Negro A, Lutolf M. 3D niche microarrays for systems-level analyses of cell fate. Nat Commun. 2014;5:4324 pubmed publisher
Basilico C, Pennacchietti S, Vigna E, Chiriaco C, Arena S, Bardelli A, et al. Tivantinib (ARQ197) displays cytotoxic activity that is independent of its ability to bind MET. Clin Cancer Res. 2013;19:2381-92 pubmed publisher
Jung D, Che Z, Kim J, Kim K, Kim K, Williams D, et al. Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7. Int J Cancer. 2010;127:332-44 pubmed publisher
Switzer C, Ridnour L, Cheng R, Sparatore A, Del Soldato P, Moody T, et al. Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity. Oncogene. 2009;28:3837-46 pubmed publisher
Tian F, Liang P, Li L. Inhibition of endothelial progenitor cell differentiation by VEGI. Blood. 2009;113:5352-60 pubmed publisher
Tahinci E, Thorne C, Franklin J, Salic A, Christian K, Lee L, et al. Lrp6 is required for convergent extension during Xenopus gastrulation. Development. 2007;134:4095-106 pubmed
product information
brand :
R&D Systems
master code :
1918-FN
SKU :
1918-FN-02M
product name :
Human Fibronectin Protein, CF
unit size :
2 mg
seo description :
The Human Fibronectin Protein, CF from R&D Systems is derived from Human Plasma. The Human Fibronectin Protein, CF has been validated for the following applications: Bioactivity.
target :
Fibronectin
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Tris-HCl, NaCl and Urea.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
gene symbol :
FN1
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of B16-F1 mouse melanoma cells. The ED50 for this effect is 35.0-420 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
applications :
Bioactivity
source :
Human Plasma
USD :
322 USD
alt names :
CIG, ED-B, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF, SMDCF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, 2 to 8 ░C as supplied. 3 months, 2 to 8 ░C under sterile conditions after opening. Avoid vortexing and excessive agitation.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.